Cardiac Imaging
Conditions
Keywords
Cardiac imaging, Cardiac CT, Cardiac MRI, Ross procedure, Loose jacket technique
Brief summary
Patients who underwent Ross procedure with loose jacket technique will be enrolled in this study and undergo CT and MRI follow-up to compare between both modalities.
Interventions
DIAGNOSTIC_TESTCardiac CT and MRI
• Cardiac MRI Protocol The cardiac MRI protocol will include cine imaging, aortic flow, and 3D navigator of the aorta. These sequences will be performed to assess aortic root dimensions, including aortic root, sinuses of Valsalva, and sinotubular junction and ascending aorta diameters. • CT Aortography Protocol: The CT aortography protocol will include non-contrast and contrast-enhanced CT imaging. The non-contrast images will be used for calcium scoring, while the contrast-enhanced images will be used to assess aortic root dimensions
Sponsors
Assiut University
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* All patients who underwent Ross procedure with loose jacket technique at Aswan Heart Centre, regardless of the indication and duration after surgery. * Patients should have survived until discharge and underwent at least one echocardiography with full data related to one or more anatomic subcomponents of the aortic root before surgery.
Exclusion criteria
* Patients who have contraindication for conducting cardiac CT scan. For instance, dye sensitivity, pregnancy, CKD, in addition to patients who have factors that interfere with CT image quality as metallic objects within the chest (e.g. Pacemaker). * Patients who have contra-indication for conducting a safe MRI scan. For instance, metallic implants that are incompatible with MRI. * Patients who underwent Ross procedure with technique other than loose jacket.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Accuracy of MRI measurements in comparison to CT using statistical analysis. | 1 year | We will use bland altman plots to visualize the degree of agreement between the two raters and identify any systematic bias. The closer the difference to zero, the better. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The largest diameters of each aortic structure | 1 year | The largest diameters of each aortic structure will be re-calculated as z-scores. In our study, significant dilatation of the aortic structures is defined as 95% confidence interval (z-score≥2) in diameter of each aortic structures. |
Countries
Egypt
Contacts
Primary ContactAbdelrahman Gamal Ahmed Ramadan, MBBCH
Outcome results
None listed