Breast Cancer, Post-Op Complication, Post-Operative Hematoma, Seroma as Procedural Complication
Conditions
Brief summary
The investigators aim to compare the incidence rates of seroma (fluid collection) and hematoma (blood clot) following breast cancer surgery between the conventional non-steroidal anti-inflammatory drug (NSAID) Ketorolac and MAXIGESIC. The investigators seek to determine the complication rates in patients receiving MAXIGESIC post-surgery, hypothesizing that the higher dosage of ibuprofen in MAXIGESIC compared to Ketorolac will result in lower complication rates.
Interventions
None listed
Sponsors
Seoul National University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Systemic performance status 0-2 according to ECOG criteria * Patients with adequate renal function: serum Cr 1.4 mg/dL or less * Patients with adequate liver function Bilirubin, AST/ALT: 1.5 times or less of the upper limit of normal, Alkaline phosphatase: 1.8 times or less of the upper limit of normal * Patients undergoing total mastectomy with SLNB or ALND (mastectomy and axillary sentinel lymph node dissection) * Patients undergoing breast-conserving surgery with ALND (mastectomy and axillary dissection) * Patients who voluntarily decided to participate in this study and signed a written informed consent form
Exclusion criteria
* Patients undergoing immediate reconstruction operation * Patients with drug allergies to painkillers and anti-inflammatory drugs * Patients with a physical condition that would interfere with understanding and submitting the consent form
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative hemovac or JP total drainage amount | within 3 months | Postoperative hemovac or JP total drainage amount |
| hematoma incidence | within 3 months | hematoma incidence |
| Seroma incidence | within 3 months | Seroma incidence |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Length of hospital stay | within 3 months | Length of hospital stay and re operation rate |
| Complication | within 3 months | * When hematoma occurs: Whether transfusion is required and whether EB band is applied, check the amount when aspirating (diagnosis criteria color: sanguinous, old bloody \[brownish\], operation (hematoma evacuation) * When seroma occurs: check the amount when aspirating (diagnosis criteria color: serous, serosanguinous) * Complication: Whether abscess occurs |
Contacts
Primary ContactJIN YOUNG BYEON
Outcome results
None listed