Major Surgery, Malnutrition, Parenteral Nutrition
Conditions
Keywords
parenteral nutrition, TPN, major surgery, malnutrition in surgery, clavien-dindo classification
Brief summary
Preoperative optimization of patients is a well known concept. Not all patients can tolerate feeds and as such TPN is given. TPN given preoperatively and continued postoperatively in selected group of patients can significantly improve the surgical outcomes and lower the morbidity as well as mortality. So the investigators aim to find the impact of TPN in malnutritional surgical patients.
Detailed description
Any patient who is at risk of malnutrition as well as already malnutritioned were given preoperative TPN for 5 days. After 5 days, elective surgery was done and TPN was continued postoperatively until patient could consume 50% of their daily requirements orally. Patients who underwent emergency surgeries were also enrolled in this study as these patients could receive TPN only postoperatively. Daily patient charting with Clavien Dindo Classification, length of stay and mortality were mentioned and verified by the operating surgical team. Data was maintained electronically by the surgical team. Data was also entered in MS-EXCEL at the time of patient discharge. Since data was maintained on everyday basis till patient discharge and does not include follow-ups, there are no missing data. Upon completion of study, all data will be exported to SPSS and analyzed accordingly using means, SDs, Chi-square and Fisher exact test.
Interventions
DIETARY_SUPPLEMENTTPN-N7 Baxter
providing TPN to all malnutrition patients preoperatively as well as postoperatively.
Sponsors
Nepal Medical College and Teaching Hospital
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* 1\. All patients who underwent major gastrointestinal surgery and received perioperative TPN or postoperative TPN
Exclusion criteria
* Perioperative TPN administration that did not follow the study protocol * TPN given for reasons other than malnutrition
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| studying the effects of TPN on length of hospital stay | through study completion, an average of 5years | comparison of perioperative and postoperative TPN in terms of mean length of stay in days |
| studying the effects of TPN on mortality | through study completion, an average of 5years | comparison of perioperative and postoperative TPN in terms of number of mortality cases |
| studying the effects of TPN on complications using grades | through study completion, an average of 5years | comparison of perioperative and postoperative TPN in terms of Clavien-Dindo classification grades |
| studying the effect of albumin levels on length of hospital stay | through study completion, an average of 5years | comparison of low and normal albumin levels in terms of mean length of stay in days |
| studying the effect of albumin levels on mortality | through study completion, an average of 5years | comparison of low and normal albumin levels in terms of number of mortality cases |
| studying the effect of albumin levels on complication using grades | through study completion, an average of 5years | comparison of low and normal albumin levels in terms of Clavien-Dindo Classification grades |
Countries
Nepal
Outcome results
None listed