Effects of Timing of Cord Clamping on Serum Calcium Levels in Neonates

Status

Recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06573333

Enrollment

200

Registered

2024-08-27

Start date

2024-01-01

Completion date

2024-09-30

Last updated

2024-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Serum Calcium Concentration

Brief summary

Title: Effect of timing of cord clamping of serum calcium levels in neonates Background: Hypocalcemia is a common metabolic problem in neonatal period. Most cases of hypocalcemia are asymptomatic however, the symptomatic cases require prompt management. Objective: The objective is to determine the effects of early and delayed cord on serum calcium level in neonates Study Design: Randomized Controlled Trial

Detailed description

Place and Duration of Study: PEMH Rawalpindi and CMH Rawalpindi from January 2024 to July 2024. Patients and Methods: Total sample size of 200 neonates will be included in the study divided into four groups with cord clamping at 15s, 30s, 60s, 120s each group will have a total of 50 neonates. Blood sampling for CBC / CRP / S. Electrolytes (Na, K, Total Ca, Ionized Ca, Mg), S Calcitonin, ABGs (HCO3 Levels) samples will be collected at 6 hours of life. * Inclusion Criteria: Neonates born at gestational age 37 weeks to 41 weeks with no maternal complication. Parents who give consent for inclusion in the study * Exclusion Criteria: Mothers with evidence of clinical disease (diabetes, preeclampsia, hypertension). Babies with congenital malformations and intrauterine growth restriction. Expected Results: Research data on serum Calcium levels in neonates have shown no correlation to timing of cord clamping. Same results are expected in this study.

Interventions

PROCEDUREUmblical Cord Clamping

Umbilical Cord will be clamped using a plastic clamp at the noted time after delivery of the neonate

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Caregiver, Investigator)

Intervention model description

Randomised Controlled Trails

Eligibility

Sex/Gender

ALL

Age

1 Minutes to 6 Hours

Healthy volunteers

Yes

Inclusion criteria

* Neonates born at gestational age 37 weeks to 41 weeks with no maternal complication. Parents who give consent for inclusion in the study

Exclusion criteria

* Mothers with evidence of clinical disease (diabetes, preeclampsia, hypertension). Babies with congenital malformations and intrauterine growth restriction.

Design outcomes

Primary

Measure	Time frame	Description
Effects of Timing of Cord Clamping on Serum Calcium Levels in Neonates	at 6 hours of life	Serum Calcium Levels

Countries

Pakistan

Contacts

Primary ContactUmair Qureshi, MBBS

umairanees94@gmail.com0519273480

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026