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Preoperative Gluteal Muscle Atrophy: A Silent Predictor of THA Dislocation.

Preoperative Gluteal Muscle Atrophy: A Silent Predictor of THA Dislocation.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06571604
Enrollment
72
Registered
2024-08-26
Start date
2020-01-01
Completion date
2023-05-01
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dislocation, Muscle Degeneration, Total Hip Arthroplasty

Keywords

Total Hip Arthroplasty, Muscle Fatty Degeneration, CT, Gluteal Muscles

Brief summary

This study looks at how fat buildup in hip muscles relates to hip osteoarthritis and less favorable recovery after hip replacement surgery. While it is known that weak gluteal muscles might cause problems, it is not yet proven if this specifically leads to hip dislocation after surgery. The goal of this study is to compare fat buildup in gluteal muscles between patients who had a hip dislocation soon after surgery and those who did not.

Interventions

DIAGNOSTIC_TESTDislocation

One episode of total hip dislocation diagnozied on Xray within 2 years of surgery

DIAGNOSTIC_TESTNo dislocation

No experience of dislocation within two years post-surgery

Sponsors

Centre Hospitalier Universitaire de Nīmes
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* primary THA with preoperative CT-scan

Exclusion criteria

* malposition of acetabular implants outside the Lewinneck safe zone, * neurological or cognitive disorders, * associated spinal pathologies (within the context of a hip-spine syndrome), * chronic alcoholism, * aseptic osteonecrosis, * revision surgeries, * late dislocations attributed to polyethylene wear, * replacement following post-traumatic coxarthrosis due to acetabulum injuries. * diameters of the prosthetic heads ≠ 32mm

Design outcomes

Primary

MeasureTime frameDescription
Mean Attenuation RatioThe CT scan of the pelvis used to plan the operation is performed between one and two months before the surgery.The mean attenuation ratio (MAR), representing muscle fat degeneration, corresponds to the mean grayscale pixels in the selected area, expressed in Hounsfield Units (HU). Subsequently, the segmentation process was applied, selectively retaining pixels within the range of -30 HU to 150 HU. This range corresponds to muscle fibers and intramuscular fat, effectively excluding extra-fascial fat and bone pixels.

Secondary

MeasureTime frameDescription
Cross-Sectional AreaThe CT scan of the pelvis used to plan the operation is performed between one and two months before the surgery.The cross-sectional area (CSA), measured in square centimeters (cm²) defines the average muscle surface area.
Intramuscular Fatty FractionThe CT scan of the pelvis used to plan the operation is performed between one and two months before the surgery.Finally, the intramuscular fatty fraction (IFF) or percentage of intramuscular fat was calculated using the IB Delta Suite plug-in with thresholds of -30/0/150. Pixels below -30 HU and above 150 HU were designated as extra-muscular, while pixels ranging between 0 HU and 150 HU represented muscle fibers. Pixels falling between -30 HU and 0 HU denoted intramuscular fat, constituting the IFF.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026