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The Immediate Effect of Combined Terminal Knee Extension Exercise With Audible Cues

The Immediate Effect of Combined Terminal Knee Extension Exercise With Audible Cues on Vastus Medialis Muscle Motor Unit Behavior in Healthy Individuals

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06565325
Enrollment
30
Registered
2024-08-21
Start date
2024-02-10
Completion date
2025-03-07
Last updated
2025-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle Weakness

Keywords

Terminal Knee Extension Exercise, Audible Cues, Therapeutic exercise, Muscle strength

Brief summary

Typically, patients perform TKE by themselves after exercise prescription. The investigators thought that a lack of attention and preferred speed of patients might not provide the best outcome. Therefore, an increased effectiveness of TKE is interesting for physical therapy implication. Besides, adding sensory input which is audible cues or rhythm during exercise may enhance the efficacy of the exercise by increasing neuromuscular control and function. Therefore, the study aimed to investigate the immediate effects of combined TKE with audible cues on motor unit behavior. The researchers expect that adding rhythm from the metronome will enhance neuromuscular control which may change motor unit behavior of VM muscle. The findings of the study may have helped explain the mechanism behind the acute effects of combined TKE with audible cues on VM function and their potential application in the field of physical therapy. This study aims to investigate the immediate effect of combined TKE with audible cues on motor unit behavior in healthy participants and to investigate reliability of decomposition electromyography procedure during single leg squat.

Detailed description

A metronome will be used to provide rhythmic exercise. Participants will stand with their feet in line with their shoulders as starting position and straping at the knee. Exercise intensity is 60% of the 1RM weight. At the beginning of the exercise, participants will be asked to bend their knees following the pull of the resistance and exert force to straighten the knee (10 times/set and 3 sets). 180 seconds of resting will be allowed between sets.

Interventions

BEHAVIORALExercise + Audible Cues

Combined Terminal Knee Extension Exercise with Audible Cues

BEHAVIORALExercise

Terminal Knee Extension Exercise

Sponsors

Mahidol University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Masking description

Participant group

Intervention model description

There are 2 groups in the current study including exercise with and without audible cues.

Eligibility

Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
No

Inclusion criteria

* Aged range between 18 and 30 years * BMI of 18.5-25 kg/m2 * Male or female * Lightly active or sedentary {Physical activity level (PAL= 1.4-1.69)}

Exclusion criteria

* History of serious injury or operation of lower back and lower extremities such as fracture * Musculoskeletal problems of lower back and lower extremities in 6 months before the study * Single-leg stance test \< 43 seconds (26). and range of weight-bearing lunge test \< 9.1 cm

Design outcomes

Primary

MeasureTime frameDescription
Motor unit firing rateAt the end of Cycle 1 (each cycle is 1 day)one parameter to explain the motor unit behavior of vastus medialis muscle
Peak motor action potentialAt the end of Cycle 1 (each cycle is 1 day)one parameter to explain the motor unit behavior of vastus medialis muscle

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026