Development, Standardisation and Standardisation Project for a New Memory Assessment

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06564779

Acronym

NEM

Enrollment

150

Registered

2024-08-21

Start date

2024-11-22

Completion date

2028-11-01

Last updated

2026-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Memory Disorders

Keywords

Alzheimer, Episodic memory

Brief summary

Episodic memory (EM) is a neuropsychological marker of Alzheimer's disease (AD) (Thomas-Anterion, 2006). Current tests for its assessment do not take into account the identity and emotional aspects of memory (Van der Linden et al., 2018). However, there are models that integrate links with identity, self-awareness and experience. Pause et al. (2013) propose criteria to create ecological tools, including consideration of the emotional valence of memories and the spatio-temporal context of acquisition. In line with these criteria, we have developed a new tool: the NEM (New evaluation of Episodic Memory). Preliminary studies show different response profiles on the NEM among patients (Launay et al., 2023). We now want to evaluate the relevance of this tool in the differential diagnosis of AD.

Interventions

OTHERNew memory assessment

The intervention is part of the neuropsychological assessment carried out as part of routine care. It consists of carrying out the neuropsychological tests traditionally used to investigate the diagnostic hypothesis of Alzheimer's disease.

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

50 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age ≥ 50 years * Ability to understand judged sufficient by the assessor; * Amnesic MCI profile (Petersen, 2003) during the 1st medical consultation prior to the assessment being prescribed.

Exclusion criteria

* Severe auditory and/or visual sensory impairment not compatible with neuropsychological assessment; * Judged fit to take the test by the assessor; * Patient under guardianship, curatorship or family guardianship; * Opposition to data processing.

Design outcomes

Primary

Measure	Time frame	Description
Score total NEM (new memory assessment)	baseline	Sum of the episodic elements

Secondary

Measure	Time frame	Description
NEM sub-scores	baseline	Sum of the episodic elements by category
Total RL/RI 16 Recall	baseline	(Van der Linden et al., 2014)
Delayed Mem Logic Recall	baseline	(MEM IV, Wechsler, 2014)

Countries

France

Contacts

CONTACTAlix LAUNAY

a.launay@chu-tours.fr0247470458

PRINCIPAL_INVESTIGATORAlix LAUNAY

Tours University Hospital

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 1, 2026