Ankle Sprains
Conditions
Keywords
Range of motion, Numerical Rating Scale
Brief summary
The aim of this study is to evaluate the short-term effects of routinely applied agents on pain and joint range of motion (ROM) in ankle sprains presenting to the emergency department (ED).
Detailed description
It is aimed to examine the effects of intravenous (IV) 50 mg dexketoprofen, IV ibuprofen 400mg and IV paracetamol 10 mg on pain and joint range of motion. To determine the effects of these agents on pain, the easily applicable Numerical Rating Scale (NRS) and Wong-Baker Faces Pain Rating Scale will be used. A standard handheld half-circle goniometer will be utilized to calculate active ankle joint ROM.
Interventions
DRUGDexketoprofen Trometamol 50 Mg/mL Solution for Injection
Dexketoprofen 50 mg administered parenterally (intravenously in 150 cc isotonic saline over 15 minutes infusion).
DRUGIbuprofen 100 MG/ML Solution for Injection
Ibuprofen 100 mg/ml administered parenterally (intravenously in 150 cc isotonic saline over 15 minutes infusion). Group P: Paracetamol 10 mg/ml administered parenterally (intravenously in 150 cc isotonic saline over 15 minutes infusion).
DRUGParacetamol 10 Mg/mL Solution for Injection
Paracetamol 10 mg/ml administered parenterally (intravenously in 150 cc isotonic saline over 15 minutes infusion).
DRUGisotonic saline
Ibuprofen and dexketoprofen will be administered intravenously (IV) by mixing them into 150 cc of isotonic saline.
Sponsors
Ankara Etlik City Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Adults aged 18 years and older who present to the emergency department within the first 72 hours after ankle sprain. * Grade 1 (mild) and Grade 2 (moderate) ankle sprains. * Exclusion of fractures and dislocations (after X-ray according to Ottawa rules). * Absence of muscle-tendon ruptures. * Absence of vascular and nerve injuries. * Absence of open wounds and burns. * Stable vital signs. * Patients who provide written and verbal consent.
Exclusion criteria
* Patients who did not present to the emergency department within the first 72 hours after ankle sprain. * Grade 3 (severe) ankle sprains. * Multiple traumas. * Pregnancy or suspected pregnancy. * Ankle fractures and dislocations. * Forensic cases. * History of previous ankle surgery or fracture.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| To evaluate the effectiveness of multimodal treatment methods on pain in ankle sprains. | *Patient's pain level, NRS Scale: - 0 minute before treatment -15 minute after treatment -60 minute after treatment | Numeric Rang Scale (NRS) will be used to assess effects on pain. NRS: This scale uses 11 numbers from 0 to 10 to measure pain intensity, where 0 represents No pain and 10 represents Worst (unbearable) pain. |
| To evaluate the effectiveness of multimodal treatment methods on Range of Motion in ankle sprains. | - 0 minute ROM before treatment - 60 minute ROM after treatment | A standard handheld goniometer will be used to calculate Range of Motion (ROM) measurements. The aim is to determine the effects of multimodal treatment methods routinely applied in emergency services on pain and range of motion and to reveal their superiority over each other, if any. (Normal ROM values: 20° for dorsiflexion, 45° for plantar flexion) |
Countries
Turkey (Türkiye)
Outcome results
None listed