Obese
Conditions
Keywords
High-Flow Nasal Oxygen, Obese Men, Smoking
Brief summary
There is a risk of airway-related incidents during anaesthesia associated with obesity. High-flow nasal oxygen is advocated for perioperative preoxygenation in obese patients to reduce airway adverse reactions. However, there have been no reports on whether smoking behaviors have an impact on obese men's Apnoeic oxygenation with high-flow nasal.This study compared the effects of smoking on the duration of safe apnoea times in obese males.
Detailed description
All patients were were divided into two groups based on smoking status: smokers(S groups), and never smokers(NS groups). Those in the smoking group were current smokers, while those in the nonsmoking group had never smoked. Both groups of patients were induced with intravenous anesthesia and received 5 minutes of high flow nasal oxygen (60 L min) prior to induction.After induction of anaesthesia, the patients were apnoeic until peripheral oxygen saturation decreased to 95 %.
Interventions
DEVICEapnoeic
In group S, High-Flow Nasal Oxygen was performed after the patient lost spontaneous breathing until the end-expiratory oxygen concentration reached 95 %.
Sponsors
Henan Provincial People's Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Masking description
A total of 60 male obese patients undergoing elective non-thoracic surgery were divided into two groups (n=30) based on smoking status: smokers(S groups), and never smokers(NS groups). Those in the smoking group were current or past smokers, while those in the nonsmoking group had never smoked.
Intervention model description
A total of 60 male obese patients undergoing elective non-thoracic surgery were divided into two groups (n=30) based on smoking status: smokers(S groups), and never smokers(NS groups). Those in the smoking group were current or past smokers, while those in the nonsmoking group had never smoked.
Eligibility
Sex/Gender
MALE
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
1. Participants ranged in age from 18 to 80 with BMI≥30 kg/m2. 2. Participants are male obese patients undergoing elective non-thoracic surgery
Exclusion criteria
: 1. patients were kept awake during the intubation due to cervical spine pathology. 2. Patients with unstable hemodynamics. 3. Patients with airway inflammatory diseases, including asthma, chronic obstructive pulmonary disease (COPD), lung cancer, pulmonary fibrosis and cystic fibrosis. 4. Patients with upper respiratory infection and nasal blockage. 5. Patients with Hypersensitivity to the drug.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the safe apnoea times | 5-minute | Investigators will record the time of oxygen saturation drop to 95 % during intubation. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the Pao2 levels | 5-minute | the Pao2 levels after 5-minute pre oxygenation with high flow nasal oxygen in two groups of patients. |
Countries
China
Contacts
Primary Contacthuabing wang
Backup Contactjiaqiang zhang
Outcome results
None listed