Burn Injury, Burns, Inhalation Injury
Conditions
Brief summary
The aim of this observational study is to investigate the role of the glucose-potassium ratio in predicting mortality in patients with major burn trauma. The main question it aims to answer is: Can the glucose-potassium ratio predict mortality in major burn patients? The glucose-to-potassium ratios of major burn patients at the time of initial hospitalization will be determined, and their relationship with mortality will be analyzed.
Detailed description
Major burns, especially electrical burns, facial burns, inhalation burns, burns with large burn surface areas, and deep burns, have a high mortality risk. Early detection of this risk may be critical to reducing mortality rates. For this reason, trauma centers are working on rapid and effective prognostic markers. In trauma and stress situations, glucose levels rise while potassium levels fall due to increased catecholamines. The literature reports that hyperglycemia, also known as the glucose-potassium ratio, can rapidly and effectively predict morbidity and mortality in patients suffering from subarachnoid hemorrhage, pulmonary embolism, traumatic brain injury, or blunt abdominal trauma. Many publications show that increased glucose is associated with mortality and morbidity in critical illnesses and trauma. The isolated glucose-potassium ratio has a higher predictive ability for mortality and morbidity compared to glucose and potassium levels. In this study, investigators aimed to examine the prognostic value of the glucose-to-potassium ratio in participants with major burn trauma.
Interventions
None listed
Sponsors
Konya Meram State Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* All burns \>40% of total body surface area (2nd degree or deeper) * Burns with inhalation injury * Burns \>20% of total body surface area 3nd degree or deeper
Exclusion criteria
* First degree burns * Patients have more than 24 hours since the onset of burn trauma * Patients with diabetes mellitus * Patients with chronic renal failure * Patients taking potassium-modifying medication * Patients with missing data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Glucose-to-potassium ratio | 2 days | The glucose-to-potassium ratio is calculated by dividing the participants' glucose values when they first apply to the hospital by their potassium values. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Female/Male ratio | 2 days | It is calculated by dividing the number of females by the number of males in the study population. |
| Mean percent of total body surface area burned | 2 days | It is calculated by adding the total burn surface area percentage values of all patients and dividing by the number of participants. |
| Burn infection rate | 2 days | The number of patients developing burn infection is calculated by dividing by the number of all participants. |
| Mortality rate | 2 days | The mortality rate is calculated by dividing the number of patients who developed mortality by the number of all participants. |
Countries
Turkey (Türkiye)
Outcome results
None listed