LAPAROSCOPIC CHOLECYSTECTOMY
Conditions
Brief summary
For patients with symptomatic cholelithiasis, laparoscopic cholecystectomy (LC) is a customary procedure for treatment these days. After LC, patients may experience considerable pain. This study was performed with the objective of comparing the mean duration of analgesia of intraperitoneal bupivacaine with dexmedetomidine to intraperitoneal bupivacaine alone in patients undergoing laparoscopic cholecystectomy.
Interventions
DRUGBupivacaine injection
patients received intraperitoneal bupivacaine 50 ml 0.25% + 5 ml normal saline.
DRUGDexmedetomidine injection
Patients were given intraperitoneal bupivacaine 50 ml 0.25% + dexmedetomidine 1 μg/kg with normal saline 5 ml.
Sponsors
Bahawal Victoria Hospital
RESnTEC, Institute of Research
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Patients of either gender * Aged between 20 and 70 years * ASA (American Society of Anesthesiologists Classification) physical status I and II * Undergoing Laparoscopic Cholecystectomy under general anesthesia
Exclusion criteria
* Patients sensitive to local anesthetics * Patients with acute cholecystitis, choledocholithiasis, or ascending cholangitis (temperature≥38.6°C, serum bilirubin≥1.2mg/dl, and ultrasound showing common bile duct diameter of ≥1cm). * Patients with uncontrolled diabetes (FBS≥110 mg/dl) * Uncontrolled blood pressure (SBP≥140 mmHg) * Ischemic heart disease (EF≤40%) * Pulmonary dysfunction (FEV≤70 percent of normal)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Duration of analgesia | 24 hours | The duration of postoperative analgesia was calculated as the time in minutes starting after the dressing of the patient in the operation room until the patient had a VAS≥3. |
Countries
Pakistan
Outcome results
None listed