Clinical Characteristics and Surgical Outcomes of Full-thickness Macular Hole Without Focal Vitreomacular Traction.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06560710

Enrollment

100

Registered

2024-08-19

Start date

2016-12-01

Completion date

2024-07-31

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Macular Holes

Keywords

macular hole, epiretinal prolidferation, vitrectomy

Brief summary

This multicenter, retrospective, observational comparative study. We occasionally encounter FTMHs in which PVD has not been achieved and VMT is absent. These FTMHs cannot be defined by stage in the Gass1) or IVTS3) classification. It is not known whether traction is involved in the development of these atypical macular holes, but they are often classified as Gass stage 2 or 3 according to the size of the hole. The aim of this study was to investigate the clinical features and surgical outcomes of FTMHs without focal VMT and to discuss possible underlying mechanisms.

Detailed description

The clinical characteristics and surgical outcomes the patients diagnosed with FTMH without focal VMT in the macula (classified as VMT-) are presented, in addition to a comparative analysis of the patients presenting with classic stage 2 FTMH with focal VMT (classified as VMT+) according to international classification criteria.

Interventions

OTHERvitrectimy

Clinical characteristics and surgical outcomes

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

19 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

\- macular hole without posterior vitreous detachment at the fovea

Exclusion criteria

* macular hole with posterior vitreous detachment at the fovea * Stage1.3.4 macular hole * Macular hole-associated retinal detachment * Macular hole with subretinal hemorrhage * Traumatic MH

Design outcomes

Primary

Measure	Time frame	Description
postoperative visual acuity	1month, 3, 6 and 12 months	logMAR visual acuity

Secondary

Measure	Time frame	Description
postoperative status of outer retinal layer in OCT B-scan images	1month, 3, 6 and 12 months	External limiting mambrane, Elipsoid zone, Interdegitaion zone

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026