Evaluation of Postoperative Intracranial Pressure in Patients Undergoing Intracranial Tumor Surgery

Comparison of Two Methods Used to Asses Postoperative Intracranial Pressure in Patients Undergoing Intracranial Tumor Surgery

Status

Not yet recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06559566

Enrollment

Registered

2024-08-19

Start date

2024-09-15

Completion date

2025-05-01

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

INTRACRANIAL PRESSURE, INTRACRANIAL TUMOR, OPTIC NERVE

Keywords

OPTIC NERVE, INTRACRANIAL PRESSURE, INTRACRANIAL TUMOR, INTRACRANIAL TUMOR SURGERY, Intracranial Pressure Change

Brief summary

Ultrasonography(USG)-guided optic nerve sheath diameter measurement and its correlation with brain computed tomography in the evaluation of intracranial pressure in patients who underwent intracranial brain tumor surgery.

Detailed description

Optic Nerve Sheath Diameter (ONSD) Measurement is a non-invasive diagnostic method used to detect increased intracranial pressure, and in general, ONSD measurement over 5 mm has been found to be associated with increased intracranial pressure.ONSD will be measured using an USG device within the specified time periods. T0: Before anesthesia induction T1: First 5 minutes immediately after induction of anesthesia T2: At the end of the surgery before extubation /minute T3: Within the first hour/minute after extubation T4: 12 hours/minute after tumor resection T5. 24 hours/minute after tumor resection ONSD measurement in brain computer tomography (BCT); Eyeball diameter and optic nerve diameter measurements will be made on BCT transverse images at the optic nerve level and recorded.In patients, USG and BCT correlation comparison is planned before the operation (T0), in the first hour after the end of post-operative surgery (T3) and at the 24th hour after post-operative surgery (T5). T0: ONSD measurement in pre-operative Brain CT T3: BCT ONSD measurement/minute within the first hour following the postoperative period T5: BCT ONSD measurement/minute 24 hours following the postoperative period

Interventions

PROCEDUREUSG

The aim of this study is to measure the intracranial pressure of patients planned for brain tumor surgery by measuring the optic nerve sheath diameter (ONSD) under USG guidance and compare its correlation with the computed brain tomography.

PROCEDUREBCT

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Patients over 18 -65 years * Brain malignant neoplasm tumor * Brain benign neoplasm supratentorial * Brain benign neoplasm infratentorial information

Exclusion criteria

* Patients who cannot provide adequate image quality in ocular ultrasonography * Who are unconscious or have a Glasgow coma scale of less than 15 * Pseudotumor cerebri * Optic nerve arachnoid cyst * Patients with open injuries involving the eyelid and surrounding area * Optic nerve malignant neoplasm * Injury of the optic nerve and its pathways * Systemic Lupus Erythematosis, * Scleroderma * Multiple Sclerosis, sarcoidosis * Thyrotoxicosis (hyperthyroidism)

Design outcomes

Primary

Measure	Time frame	Description
intracranial pressure	T0: Before anesthesia induction T1: peroperative5. minutes T2: At the end of the surgery 6.hours T3:after extubation 1 hours T4: postoperative 12.hours T5. postoperative 24.hours	To compare the optic nerve diameter measurement ,USG and BBT values used to measure intracranial pressure in patients with brain tumor surgery

Secondary

Measure	Time frame	Description
Heart Rate	T0: Before anesthesia induction T1: preoperative 5.minutes T2: At the end of the surgery 6.hoursT3:after extubation 1 hours T4: postoperative 12.hours T5. postoperative 24.hours	To compare the heart rate measurement
Blood pressure	T0: Before anesthesia induction T1: preoperative 5.minutes T2: At the end of the surgery 6.hours T3 extubation 1 hours T4: postoperative 12.hours T5. postoperative 24.hours	To compare the blood pressure measurement

Contacts

Primary ContactSEZEN KUMAS SOLAK, MD

sezenkumassolak@gmail.com+905055729494

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026