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Protocol for Evaluating Physiological and Psychological Adaptation Mechanisms in Tibetan Plateau Environments

Protocol for Evaluating Physiological and Psychological Adaptation Mechanisms in Tibetan Plateau Environments: A Clinical Study of Doctors From Peking Union Medical College Hospital

Status
Enrolling by invitation
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06557928
Enrollment
17
Registered
2024-08-16
Start date
2024-05-17
Completion date
2027-12-01
Last updated
2024-08-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High Altitude

Keywords

high altitude, adaptation, acclimatization

Brief summary

This study is a single-center prospective observational study. It plans to use a series of physiological and medical instruments and international common physiological and psychological questionnaires. To dynamically detect the changes of physiological and psychological adaptability of doctors in Peking Union Medical College Hospital before leaving Beijing, 1-7 days after arriving at the plateau in Tibet during the acute phase of plateau hypoxic stress, 2 weeks, 3 months, 6 months, 12 months after staying in Tibet during the chronic phase of plateau hypoxic stress, and after returning to Beijing.

Interventions

Measurement of multiple physiological indicators and psychological status and multi-omics study

Sponsors

Peking Union Medical College Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy individuals aged 20-65 years * They can sign a written informed consent and is willing to cooperate * They have the qualification to aid Tibet and meet the basic requirements of physical examination for aid to Tibet

Exclusion criteria

* Age less than 20 years or more than 65 years * Unable to sign a written informed consent or unwilling to cooperate * They do not have the qualification for supporting Tibet or do not meet the basic requirements of medical examination for supporting Tibet

Design outcomes

Primary

MeasureTime frameDescription
help understand the physiological mechanisms and psychological changes of hypoxic adaptation2024-5-27~2026-12-1This study is expected to increase our understanding of the physiological mechanisms and psychological changes of hypoxic adaptation mainly through analysis of multi-omics.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026