Pulp Necroses
Conditions
Keywords
Root canal
Brief summary
The purpose of this study is to compare the efficacy of GentleWave versus EdgePro irrigation in the disinfection of infected root canals of human permanent teeth with necrotic pulp.
Interventions
DEVICEGentleWave
Root canals will be shaped using a Vortex Blue and ProTaper gold rotary system. Once the root canals have been shaped, the GentleWave procedure will be performed
DEVICEEdgePro laser irrigation
Root canals will be shaped using a Vortex Blue and ProTaper gold rotary system. Once the root canals have been shaped, the EdgePro procedure will be performed
DEVICEIrrisafe passive ultrasonic irrigation
Root canals will be shaped using a Vortex Blue and ProTaper gold rotary system. Once the root canals have been shaped, the passive ultrasonic irrigation procedure will be performed
Sponsors
The University of Texas Health Science Center, Houston
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Permanent teeth that are diagnosed with pulp necrosis. * elected to have a permanent tooth nonsurgical root canal treatment * Signed informed consent.
Exclusion criteria
* Teeth with root fractures or previously root canal treated teeth. * Teeth with severe loss of structure * Teeth with vital pulps.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bacterial count reduction checked by 16 S rDNA next-generation sequencing analysis (NGS) | Baseline, after cleaning and shaping of the root canal (about 30 minutes after baseline) |
Secondary
| Measure | Time frame |
|---|---|
| Presence of proteolytic versus non-proteolytic bacteria in the root canals | Baseline, after cleaning and shaping of the root canal (about 30 minutes after baseline) |
Countries
United States
Contacts
Primary ContactDavid Jaramillo, DDS
Backup ContactAhmed Shehab-Eldin
Outcome results
None listed