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EndoStyle: Artificial Intelligence Image Transformation Tool for Colonoscopy

EndoStyle: Survey of Physicians on Endoscopic Image Style Transfer.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06553326
Acronym
EndoStyle
Enrollment
40
Registered
2024-08-14
Start date
2024-08-15
Completion date
2025-08-22
Last updated
2025-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon Cancer, Colon Rectal Cancer

Keywords

colonoscopy, Artificial intelligence

Brief summary

The study addresses the limitations of current AI systems in gastrointestinal endoscopy, which are tipically trained with data from a single type of endoscopy processor and have limited expert-annotated images. The investigators aim to develop and validate EndoStyle, an AI system that can generate images in the style of various processors from a single reference image. EndoStyle will be tested by showing endoscopists colonoscopy sequences with different image types to determine if they can distinguish AI-transformed images. Success would enhance AI training for diverse clinical setups.

Detailed description

The use of artificial intelligence (AI) in gastrointestinal endoscopy has become widespread. However, these systems are often only trained with data from a single type of endoscopy processor, which limits their applicability. In addition, the availability of images annotated by experts is limited, which affects data variability and thus the performance of AI systems. The aim of this study is to develop a new artificial intelligence (AI) based system (EndoStyle) and validate its authenticity by means of a survey among physicians, which is able to generate multiple images in the style of different processor types (including Olympus, Pentax and Storz) from a single endoscopy reference image. The investigators hypothesis is that the AI system is able to successfully change the image style of video processors, with the differences being imperceptible to the endoscopist's eye. The methodology consists of showing to multiple endoscopists 28 colonoscopy sequences of 10 seconds duration each. In each one of them 3 images will be shown that can be all the possible combinations of images belonging to positive control, negative control, and Endostyle (intervention group). By performing a statistical comparison of the percentages of selected images for each group the investigators will be able to establish whether the participants are able to distinguish the images transformed by the AI. If the results corroborate our hypothesis, our system could generate images that would allow a more customized training of AI systems for each clinical setup.

Interventions

DEVICEEndoStyle

The EndoStyle system is able to transform the style of the different video-processor images.

Sponsors

Wuerzburg University Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Physicians with experience in colonoscopy.

Design outcomes

Primary

MeasureTime frameDescription
Perceptual Indistinguishability of AI-Transformed Endoscopic Images5 monthsComparison of the accuracy for each study group.

Secondary

MeasureTime frameDescription
Time Taken for Image Identification5 monthsTime taken to assess the different tasks according to each study group.
Influence of regularly used processor5 monthsInfluence of regularly used endscopy processor during clinical work for the perceptual indistinguishability of AI-transformed endoscopic images with defined processor classes
Influence of endoscopy experience5 monthsInfluence of experience in endoscopy measured in lifetime performed colonscopies on perceptual indistinguishability of AI-transformed endoscopic images

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026