Tooth Extraction
Conditions
Keywords
Tooth socket, Laser, wound healing, bone regeneration, pain
Brief summary
The goal of this clinical trial is to learn if the laser works to improve wound healing and bone regeneration after tooth extraction. The main question it aims to answer is: Does laser therapy improve wound healing and bone regeneration after tooth extraction? Researchers will compare a laser to sham laser therapy to see if the laser enhances wound healing and bone regeneration. Participants will: Have exposure to laser or sham laser therapy immediately after tooth extraction Record their pain intensity on days 2, 4, 6 and 14 Visit the clinic after 10 days for follow-up Again, visit the clinic after 4 months for evaluation
Interventions
OTHERDiode Laser 980 nm.
A Diode laser is commonly used in simple surgical procedures on soft tissue, such as skin or mucosa. Its tip can work when non-activated, causing inductive effects, and when activated, it causes the ablation of soft tissue.
Sponsors
Universiti Sains Malaysia
Sharif Medical Research Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* At least 21 years old, regardless of gender * Non-traumatic tooth extraction of the lower jaw is indicated * Willing for dental implant surgery * Dental appointments are available at the study place * Absence of active infection at the extraction site * Signed informed permission is provided.
Exclusion criteria
* Pregnant, lactating, and menopausal women * Smokers * Those having head and neck radiotherapy * Those with any sort of acute infection (e.g., periodontal abscess), immune deficiency, or metabolic conditions such as diabetes mellitus and osteoporosis * Patients will also be eliminated if they have a complication during surgery, such as bleeding or operational difficulties, or if the procedure takes longer than 90 minutes.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Wound healing will be assessed in both the experimental and control groups. | 1 year | Wound healing will be assessed using the Landry, Turnbull, and Howley index after 7 days, and a score will be given ranging from 1 to 5, where 1 indicates very poor healing, and 5 indicates excellent healing. (score range: 1-very poor, 2-poor, 3-good, 4-very good, 5-excellent) |
| Bone regeneration will be assessed in both the experimental and control groups. | 1 year | A postoperative cone beam computed tomography (CBCT) will be taken immediately after extraction, followed by a CBCT 4 months after extraction. The immediate CBCT will be done to study the density of healthy bone in the apical region of the extracted tooth socket. This value will serve as the baseline for further assessment. The density obtained will then be compared with the bone formed at the end of 4 months in the extraction socket with and without laser therapy. Taking mean readings in the grayscale measurements from the periapical region will allow for the calculation of bone density. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain intensity will be measured in both the experimental and control groups. | 1 year | The Visual Analogue Scale (VAS) will assess pain intensity at post-extraction days 2, 4, 6, and 14. It consists of a 10 cm line with two endpoints representing 0 ('no pain') and 10 ('pain as bad as it could possibly be'). VAS is a system that classifies a score of 1 to 4 (on a 0-10 scale) as mild pain, 5 to 6 as moderate pain, and 7 to 10 as severe pain. |
Countries
Pakistan
Contacts
Primary ContactProfessor
Backup ContactNauman R Khan, MPhil
Outcome results
None listed