Activation of Biobank Registry for Bilio-pancreatic Diseases

Activation of Biobank for Association Study Between Environmental and Genetic Factors in Inflammatory, Functional and Neoplastic Bilio-pancreatic Diseases

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06552078

Acronym

BIO-PANCREAS

Enrollment

2000

Registered

2024-08-13

Start date

2021-06-09

Completion date

2030-12-31

Last updated

2026-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-Neoplastic Pancreatic Disorder, Pancreatic Adenocarcinoma, Pancreatic Disease, Pancreatitis

Brief summary

The purpose of establishing the biobank is to create a collection of biological material and clinical data, with a prospective and retrospective mold, in order to investigate the role of genetic predisposition in multifactorial bilio-pancreatic diseases, so that an evaluation of the possible association in the pathogenesis of exogenous factors with endogenous factors can be allowed. Multifactorial diseases are in fact an expression of genetic predisposition upon which one or more environmental stimuli act. Usually the aforementioned factors are not capable individually of triggering disease but, when simultaneously present, can cause the pathological phenotype. Therefore, it becomes important in the description of disease pathogenesis to identify as many risk factors for disease prevention and early diagnosis.

Detailed description

Samples collected depending on the disease: * Peripheral blood; * Portal blood; * Saliva; * Urine; * Stool; * Cystic fluid; * Pancreatic juice; * Biopsy tissue specimens;

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* age \>= 18 years * signed informed consent

Exclusion criteria

* age \< 18 years * unwilling to sign informed consent

Design outcomes

Primary

Measure	Time frame	Description
The rate of patients with each pancreatic disorder presenting with certain exposures or certain biomarkers	Tthrough study completion, an average of 1 year	The rate of patients with each pancreatic disorder presenting with certain exposures or certain biomarkers will be evaluated by descriptive statistics and when available compared with that of subjects without such disorders (controls).

Countries

Italy

Contacts

CONTACTGabriele Capurso, MD

capurso.gabriele@hsr.it02/26436548

CONTACTLaura Apadula, MSN

apadula.laura@hsr.it02/26433979

PRINCIPAL_INVESTIGATORPaolo Giorgio Arcidiacono, MD

IRCCS Ospedale San Raffaele

Outcome results