ACHIEVE Pilot Statins for Vascular Protection

A Cluster-randomized Trial to Improve Use of High IntEnsity Statins for Vascular Protection

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06551701

Acronym

ACHIEVE

Enrollment

225

Registered

2024-08-13

Start date

2025-05-19

Completion date

2025-07-31

Last updated

2026-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ASCVD

Keywords

Statin

Brief summary

ACHIEVE aims to increase statin usage among patients with ASCVD by having a pharmacist talk to patients and providers.

Detailed description

Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death in the United States (U.S.) Statins reduce the risk of cardiovascular events by 30% in those with prior history of ASCVD. Despite being inexpensive and well-tolerated, however, statins are underused in clinical practice, particularly in patients who identify as Black. A large-scale intervention to improve evidence-based statin initiation among individuals with ASCVD is needed, particularly for the Black population. To meet this need, we aim to conduct a multi-center, pragmatic, cluster randomized, controlled trial to assess the impact of a provider- and patient-directed intervention to increase the prescription of, and adherence to, appropriate statin therapy among those with ASCVD (ACHIEVE: A Controlled trial to improve use of High IntEnsity statins for Vascular protEction). The intervention will be pharmacist-led, embedded in commercial payer systems, partnering with the National Committee for Quality Assurance (NCQA), and with a particular emphasis on improving statin use in the Black population.

Interventions

OTHERPharmacist call

Pharmacists will call patients and their providers to discuss benefits of statin use

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Patients with a diagnosis of atherosclerotic cardiovascular disease currently not treated with a moderate- high intensity statin and the providers that care for them. * Patient age 18-75

Exclusion criteria

* Hemodialysis * History of rhabdomyolysis

Design outcomes

Primary

Measure	Time frame	Description
Provider engagement as measured by recruitment	2 years	The goal is recruiting at least 25% of identified providers.
Patient engagement as measured by recruitment	2 years	The goal is to recruit at least 30% of identified patients overall and within the black population

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORChristopher Granger, MD

Duke University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 2, 2026