CAN3T - Canadian TAVI Triage Tool

A Step-Wedged Cluster Randomized Registry-Based Multi-Centre Trial to Compare the Efficacy Between the Canadian TAVI Triage Tool and Standard of Care in TAVI Patients in Ontario, Canada

Status

Not yet recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06551610

Acronym

CAN3T

Enrollment

5060

Registered

2024-08-13

Start date

2024-10-31

Completion date

2027-08-31

Last updated

2024-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Stenosis

Keywords

aortic stenosis, TAVI, Trans-catheter Aortic Valve Implantation, cardiovascular disease, Surgical Aortic Valve Replacement

Brief summary

The goal of this trial is to see if a tool that may reduce wait times will reduce bad outcomes in participants on the TAVI waitlist. The main questions it aims to answer are: * How many deaths, hospitalizations, or urgent TAVI procedures take place while participants wait * Days alive and out of hospital at 30 days and 12 weeks, total health care costs, and wait times Researchers will compare usual wait times to see if the tool reduces death, hospitalizations, and urgent procedures.

Interventions

OTHERTriage Tool

Tool that uses patient characteristics to triage patients for an earlier procedure date vs the standard of care 12 week wait for procedure.

Study design

Allocation

RANDOMIZED

Intervention model

SEQUENTIAL

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Intervention model description

Step-Wedged Cluster Randomized

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* All patients referred for TAVI who are 18 years or older at one of 11 TAVI hospitals

Exclusion criteria

* Any inpatient referrals who have an urgent inpatient TAVI on the same admission * Any referral during the 1-month transition period

Design outcomes

Primary

Measure	Time frame	Description
To assess the efficacy of using the CAN3T tool in triage compared to standard care, in TAVI patients, including: reduce wait-time adverse events, improve patient-centred outcomes, and reduce wait-time health care utilization.	From the beginning of enrollment and continuing for 32 months.	Composite of death, all-cause hospitalization or urgent TAVI (in-hospital and unplanned TAVI) on the TAVI waitlist. The waitlist period is defined as period between TAVI referral and first of either death, TAVI procedure or off list.

Contacts

Primary ContactCAN3T Project Manager

CAN3T@sunnybrook.ca416-480-4246

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026