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Evaluating Primary Suicide Prevention in Adolescents With Risk Factors

Evaluating Primary Suicide Prevention in Adolescents With Risk Factors

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06551038
Acronym
ESPAIR
Enrollment
240
Registered
2024-08-13
Start date
2025-03-11
Completion date
2028-09-30
Last updated
2025-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Suicide Prevention

Keywords

Suicide, Primary prevention, Vulnerable adolescents, Psychological distress

Brief summary

Suicide is one of the main causes of death among teenagers. Because it is preventable, primary prevention of suicide has become a public health priority, with encouraging results in promoting suicide awareness and reducing suicidal thoughts among adolescents. However, the lack of studies conducted among vulnerable populations (i.e., marginalised, disengaged and disadvantaged) is a major gap, even though these populations present an increased risk of suicidal behaviour. The aim of this project is to test the effectiveness of a brief primary suicide prevention intervention for vulnerable adolescents, using a randomised controlled trial. Vulnerable adolescents include those 1) detained in juvenile detention centres, 2) at risk of dropping out of school, 3) undergoing treatment for psychiatric disorders, 4) belonging to a sexual or gender diversity, 5) affected by chronic conditions, or 6) with relational/familial problems. The main aim is to test the effectiveness of the intervention on a composite measure of suicide awareness, psychological distress and suicidal thoughts. The project will also explore other issues that present challenges for vulnerable populations: access to primary suicide prevention and non-response bias. The study will provide relevant results to address the current lack of high-quality evidence for primary suicide prevention in adolescents.

Interventions

BEHAVIORALPrimary suicide prevention intervention

Psychoeducation workshop

BEHAVIORALArt-based control intervention

Slam poetry workshop

Sponsors

Stephanie Baggio
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
14 Years to 25 Years
Healthy volunteers
No

Inclusion criteria

* Vulnerable adolescents defined as being: 1) detained in juvenile detention centers, 2) disconnected from school, 3) in treatment for psychiatric disorders, 4) belonging to a sexual or gender minority, 5) affected by chronic conditions, or 6) with relational/familial problems. * Age 14 to 25 years old. * Good knowledge of French. * Accepting to sign the informed consent.

Exclusion criteria

* The medical/educational staff considers that the intervention will interfere with appropriate management of acute psychiatric disorder or may cause harm to self or other. * Being enrolled in another suicide prevention intervention during the study period.

Design outcomes

Primary

MeasureTime frameDescription
Composite measure of suicide awarenessOne-week post-baselineNine-item perceived suicide awareness scale (PSAS-9), assessed on a 5-point scale, score ranging from 0 to 36, with a higher score indicating a higher suicide awareness

Secondary

MeasureTime frameDescription
Knowledge of local resourcesOne-week post-baseline; three-month post-baselineSelf-developed scale on local resources, 6 binary (true/false) questions, score ranging from 0 to 6, with a higher score indicating higher knowledge of local resources
Psychological distressOne-week post-baseline; three-month post-baselineKessler Psychological Distress scale (K-6), 6-item scale is assessed on a 5-point scale, with a score ranging from 0 to 24. A higher score indicates a higher level of psychological distress.
Access to primary suicide preventionBaselineSelf-developed scale on primary suicide prevention training, 3 questions combined in a binary indicator (yes/no)
AttritionThree-month post-baselinePercentage of participants who drop out, continuous variable (0-100), with a higher percentage indicating a higher level of attrition
Composite measure of suicide awarenessThree-month post-baselineNine-item perceived suicide awareness scale (PSAS-9), assessed on a 5-point scale, score ranging from 0 to 36, with a higher score indicating a higher suicide awareness
Knowledge on suicideOne-week post-baseline; three-month post-baselineLiteracy of Suicide Scale (LOSS), 12 binary (true/false) questions, score ranging from 0 to 12, with a higher score indicating higher knowledge on suicide
Suicidal thoughtsOne-week post-baseline; three-month post-baselineSuicidal Ideation Attributes Scale (SIDAS), 10 questions assessed on a 5-point scale, with a score ranging from 0 to 50. A higher score indicates a higher level of suicidal thoughts.

Other

MeasureTime frameDescription
Self-reported distress (safety outcome)One-week post-baselineComposite outcome with two questions from Bailey et al. (2017, https://https://doi.org/10.1027/0227-5910/a000465) related to the distressing and pleasurable nature of the intervention, assessed on a 5-point scale, score ranging from 0 to 8, a higher score indicating higher self-reported distress
Number of participants with serious adverse events (safety outcome)One-month post baselineDeath, life-threatening event, and hospitalisation
Number of participants with adverse events (safety outcome)One-month post baselineScarification, insomnia, appetite problems, substance use, and para-suicidal endangerment behaviors identified and reported by the local team

Countries

Switzerland

Contacts

Primary ContactStéphanie Baggio, Prof.
stephanie.baggio@unibe.ch+41316846774

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026