Human Papilloma Virus, Infertility, Female
Conditions
Brief summary
The prevalence of the papilloma virus in the general population is 12%. This virus is known to impair male fertility but its impact on female infertility remains uncertain. This is a public health problem since there is a vaccination protocol. Demonstrating the impact of the human papillomavirus on fertility would be an argument in favor of vaccination.
Detailed description
This is a single-center prospective study in the assisted reproduction center of Brest University Hospital. All new patients coming to consult will be offered participation in the study. The HPV test will be updated if it is older than 12 months. We will analyze stimulation results and pregnancy outcomes according to HPV status. Inclusions will take place over 3 years
Interventions
None listed
Sponsors
University Hospital, Brest
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
25 Years to 38 Years
Healthy volunteers
No
Inclusion criteria
* all etiology of infertility AMH \> ou = à 1.1 ng/ml First ou second protocol of IVF between 25 years and 37 years and 11 months
Exclusion criteria
Age \< 25 y Age \> ou = 38 y AMH \< 1.1 ng/ml patient under juridic protection rejection of participation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| clinical pregnancy rate after fresh eSET by HPV status | 1 year | A clinical pregancy is the visualisation of a gestational sac inside the uterus after 6 weeks of gestation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| IVF issues | 1 year | oocytes number, embryos number, fecondation rate, implantation rate |
| Positive HPV rate | 1 year | number of women who have a positive HPV test before IVF procedure |
Countries
France
Contacts
Primary ContactSarah BOUEE
Backup ContactAnne-Solenn JACAMON
Outcome results
None listed