Very Low Birth Weight Infant
Conditions
Keywords
very low birth weight infants, family integrated care
Brief summary
To explore the influence of multi-angle factors, including family integrated care, on extrauterine growth restriction at discharge of very low birth weight infants.
Detailed description
To explore the influence of multi-angle factors, including family integrated care, on extrauterine growth restriction at discharge of very low birth weight infants.Very low birth weight infants admitted to 17 neonatal intensive care units in 8 provinces and cities in southeast China from February 2021 to November 2023 were retrospectively included, which were divided into case group and control group according to whether there was extrauterine growth restriction (defined as the weight below the 10th percentile of children of the same age at discharge). The general situation at birth, the length of hospital stay, the incidence of complications during hospital stay, the feeding situation, the length of family participation care and the perinatal situation of the mother were compared between the two groups. The generalized linear mixed model was used to analyze the influencing factors of extrauterine growth retardation at discharge, and the results of influencing factors were visualized by GraphPad Prism 9.0 software.
Interventions
BEHAVIORALfamily integrated care
Trained NICU nurses give effective education to parents of children, and regard parents as a part of NICU team, so that they can actively provide positive care for babies instead of passive caregivers. Parents mainly participate in nursing care such as bottle feeding, changing diapers, skin contact and so on.
Sponsors
Children's Hospital of Fudan University
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
28 Weeks to 32 Weeks
Healthy volunteers
No
Inclusion criteria
1. Newborns admitted to 17 units in 8 provinces from February 2021 to November 2023; 2. Birth weight \< 1500 g, gestational age \< 32 weeks; 3. admitted in NICU within 24 hours after birth; 4. premature infants without complications (including bronchopulmonary dysplasia, retinopathy of prematurity, necrotizing enterocolitis, intraventricular hemorrhage and late-onset septicemia) at the time of admission.
Exclusion criteria
1. death occurred during hospitalization; 2. Incomplete outcome data (lack of EUGR data at discharge).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| total duration of family integrated care | From the day admitted into the NICU until day on discharge，an average of 2 months. | Trained NICU staffs effectively educate parents as part of the NICU team so that they can proactively provide active care for the baby, rather than passive caregivers. Parents are primarily involved in care such as bottle feeding, diaper changing, skin-to-skin contact and so on.We calculate total duration of family integrated care in hours. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Birth weight | assessed at birth. | birth weight in grams |
| Small for gestational age | assessed at birth. | birth weight\<10th percentile of the neonatal growth curve for infants of the same sex and gestational age |
| Necrotizing enterocolitis | From the day admitted into the NICU until day on discharge, an average of 2 months. | diagnosed according to the Bella classification |
| gestational age | assessed at birth. | gestational age at weeks |
Other
| Measure | Time frame | Description |
|---|---|---|
| Retinopathy of prematurity | From the day admitted into the NICU until day on discharge, an average of 2 months. | diagnosed according to the International Classification of Retinopathy of Prematurity |
| Intraventricular hemorrhage | From the day admitted into the NICU until day on discharge，an average of 2 months. | the diagnosis is based on Paplie's classification |
| Late-onset sepsis | From the day admitted into the NICU until day on discharge, an average of 2 months. | sepsis occurs \>72h after birth |
| Bronchopulmonary dysplasia | From the day admitted into the NICU until day on discharge，an average of 2 months. | oxygen is required at 36 weeks of corrected gestational age or at discharge |
Countries
China
Outcome results
None listed