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The Effect of Cryostimulation on Inflammation and Motor Functions. The Study Was Conducted to Determine the Effect of Five Days of Whole-body Cryostimulation (PBC) on Reducing Inflammation and Improving Motor Skills in Soccer Players

The Influence of Cryostimulation on Reducing Inflammation and Improving Motor Skills in Football Player

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06549933
Enrollment
21
Registered
2024-08-12
Start date
2023-11-25
Completion date
2024-04-15
Last updated
2025-01-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rest, Training

Keywords

cryostimulation, regeneration, football players, inflammation, motor functions

Brief summary

The aim of the study was to determine the effect of a 5-day PBC on reducing inflammation and improving motor skills in soccer players during the initial phase of the training period. The five-day cryostimulation applied did not significantly affect the profile of inflammatory markers in soccer players. However, a reduction in visuo-motor reaction time (RT) was registered in PBC-treated soccer players, suggesting the potential benefits of this method in improving motor skills.

Detailed description

Cryostimulation is one of the methods of post-exercise recovery, involving short-term (3 min) exposure of the body to extremely low temperatures, oscillating between -100°C and -190°C. The purpose of this therapy is to reduce inflammation, reduce physical and mental fatigue and use it as a passive form of preparing the body for further exercise as part of the training process. The study was conducted to determine the effect of five days of whole-body cryostimulation (PBC) on reducing inflammation and improving motor skills in soccer players. A group of 24 football players was randomly divided into a test group (PBC; -140°C ± 20°C, 3 min, 5 days) and a control group (CON). Before the cryostimulation session, both groups were subjected to visual-motor ability tests, which were repeated on the last day of the study. Blood samples were collected at four time points (P0-1 day, P1-3 day, P2-5 day, P3-2 days after the test). Levels of creatine kinase (CK), tumor necrosis factor (TNFα), interleukins (IL-6, IL-10), testosterone (T) and cortisol (C) were determined in the samples.

Interventions

OTHERCriostymulation

Method: Cryosauna. Temperature: -160°C. Duration: 5 days. Session Timing: 9:00 a.m. Session Length: 3 minutes per day

Sponsors

Poznan University of Physical Education
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Intervention model description

Athletes undergoing regular training were divided into two groups. One of them was subjected to cryotherapy treatments, the other was a control group, not subjected to any treatments at that time.

Eligibility

Sex/Gender
MALE
Age
18 Years to 36 Years
Healthy volunteers
Yes

Inclusion criteria

* athletes * no previous experience with systemic cryotherapy * any other forms of recovery or cosmetic treatments

Exclusion criteria

* alcohol or any other stimulants * anti-inflammation drugs * injuries

Design outcomes

Primary

MeasureTime frameDescription
IL-10 (Interleukin-10)Before, after 3, and 5 days of cryostimulationImmunoenzymatic assay method using a diagnostic ELISA Kit
IL-6 (Interleukin-6)Before, after 3 days and 5 days of cryostimulationImmunoenzymatic assay method using a diagnostic ELISA Kit
TNF-alpha (Tumor necrosis factor-alpha)Before, after 3 days and 5 days of cryostimulationImmunoenzymatic assay method using a diagnostic ELISA Kit
TestosteroneBefore, after 3, and 5 days of cryostimulationImmunoenzymatic assay method using a diagnostic ELISA Kit
CK (creatine kinase)Before, after 3, and 5 days of cryostimulationImmunoenzymatic assay method using a diagnostic ELISA Kit
CortisolBefore, after 3, and 5 days of cryostimulationImmunoenzymatic assay method using a diagnostic ELISA Kit

Secondary

MeasureTime frameDescription
Anthropometric measurmentsBefore, after 3, and 5 days of cryostimulationAnalysis of body composition, Tanita BC-418

Countries

Poland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026