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Burn Coverage of Burn by Tilapia Fish Skin

Tilapia Fish Skin Coverage in Acute Thermal Burn; Experimental and Histopathological Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06549569
Acronym
TFS
Enrollment
20
Registered
2024-08-12
Start date
2022-09-01
Completion date
2024-08-01
Last updated
2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tilapia Fish Skin in Burn Coverage

Brief summary

The goal of this experimental study is to compare TFS and regular dressings as coverage for acute thermal burns. The main question it aims to answer is: Is TFS effective in treating thermal burns? burn induction was done on rabbits to obtain second-degree thermal burn, followed by coverage with TFS

Detailed description

Nile Tilapia Fish Skin (NTFS) has been suggested as an option for biological material for the management of burns. Nile Tilapia Fish Skin also presented a large composition of type I collagen, morphology similar to human skin and high resistance and tensile extension at the break. We chose Baladi rabbits for their relatively ease of handling, accommodation and resistance to surgical aggressions and infectious processes, with low mortality. However, the choice of male rabbits is due to variations in hormonal cycles in females that could intervene in the process of tissue repair. This experimental model was established to evaluate healing process and outcome results after application of Tilapia Fish Skin on acute contact thermal that was done in order to obtain injuries with the same size and depth.

Interventions

PROCEDURETFS

burn coverage with TFS

Sponsors

Aswan University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
MALE
Age
1 Years to 18 Months
Healthy volunteers
No

Inclusion criteria

\- healthy male one year old rabbit

Exclusion criteria

* female unhealthy rabbits

Design outcomes

Primary

MeasureTime frame
Tilapia Fish Skin Coverage in Acute Thermal Burn1 year

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026