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NLR and Emergency Surgery

Neutrophil-to-Lymphocyte Ratio and Mortality After Emergency Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06549101
Enrollment
851
Registered
2024-08-12
Start date
2022-09-23
Completion date
2023-12-30
Last updated
2024-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Emergency Surgery

Keywords

Neutrophil-to-lymphocyte ratio, Emergency surgery, NLR

Brief summary

In the immune system, it has been observed that the preoperative neutrophil-to-lymphocyte ratio (NLR) is an index that reflects the state of inflammation and oxidative stress. In the perioperative period, NLR has been described as a predictor for patients who will develop renal injury, ischemic stroke, and myocardial injury. Since preoperative inflammation is a predictor of morbidity and mortality in patients undergoing non-cardiac surgery, a retrospective analysis of the inflammatory status of patients undergoing surgery at the center is proposed.

Detailed description

A retrospective analysis of patients operated on at the Clinical Hospital of the University of Chile is proposed. The search will be conducted in the electronic medical records of all patients operated on between January and December 2021, with no exclusion criteria for this analysis. Demographic data, complications, length of hospital stay, and specific characteristics such as the need for mechanical ventilation, time spent in intermediate care units, and ICU as well as total hospitalization time will be recorded. For the purpose of this study, the preoperative complete blood count of the patients will be analyzed to search for hematological variables that reflect the state of preoperative systemic inflammation.

Interventions

None listed

Sponsors

University of Chile
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* Availability of complete blood count in electronic medical records of all patients operated on between January and December 2021

Exclusion criteria

* None

Design outcomes

Primary

MeasureTime frameDescription
NLRDay of surgeryPreoperative neutrophil-to-lymphocyte ratio
Mortality6 months after surgery30 and 180 days mortality

Countries

Chile

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 6, 2026