Sarcopenia
Conditions
Keywords
Sarcopsarcopenia, geriatrics, respiratory function
Brief summary
The objectives of this study are to describe the prevalence of respiratory sarcopenia, evaluate its pattern of evolution over a one-year follow-up, and determine the response to a therapeutic exercise program in older adults in a geriatric nursing clinic. A sample of approximately 115 older adults, of both sexes, from the geriatric nursing clinic of the Virgen de la Arrixaca Hospital, Murcia, will participate in the study. In the first stage, a prospective observational study will be carried out, with one year of follow-up, and subsequently a randomized controlled clinical trial, with patients who have been diagnosed with respiratory sarcopenia. In the clinical trial, patients will be divided into 3 groups: control, experimental 1 (diaphragmatic exercises) and experimental 2 (respiratory muscle training). Sociodemographic and clinical variables, physical function (palm grip, 5STS, 4MGS), respiratory function (respiratory muscle strength and diaphragmatic thickness) and health outcomes (respiratory infections, visit to the emergency department, hospitalization, falls, bedridden and/or death). Descriptive statistics, univariate and multivariate logistic regression models, Cox proportional hazards model and Kaplan-Meier curves will be used to analyze the data from the longitudinal study. To compare the differences between pre- and post-intervention of the clinical trial, a two-factor analysis of variance for repeated measures will be used. A P-value \<0.05 will be considered significant in all analyses. The recording and analysis of the data will be carried out with the IBM SPSS Statistics 24® program.
Interventions
Perform controlled and supervised diaphragmatic exercises
OTHERRespiratory muscle training
Perform respiratory muscle training with controlled and supervised devices
Sponsors
Felipe León Morillas
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* have functional ambulation (even with technical aids) * be able to obey simple commands, such as taking deep breaths * have sufficient oral occlusion capacity to perform respiratory tes
Exclusion criteria
* presence of acute respiratory diseases * serious orthopedic diseases that interfere with measurements * diagnosis of severe dementia * those who present any contraindication for performing respiratory pressure measurement tests, as established in the guidelines of the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| physical function hand grip | 24 Months | Hand grip: palm press strength |
| RESPIRATORY MUSCLE FUNCTION | 24 Months | INSPIRATORY AND EXPIRATORY PRESSURE OF THE MUSCULATURE |
| ultrasound | 24 Months | diaphragm muscle thickness |
| body composition | 24 Months | Calculation of bioimpedance |
| Physical function | 24 Months | five times sit-up test (5STS) |
| Physical function walking speed | 24 Months | walking speed (4MGS) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sociodemografic | 24 months | sex, age, marital status and educational level |
Countries
Spain
Contacts
Primary ContactSilvana L de Oliveira Sousa, Dr.
Backup ContactCarmelo S Gómez Martínez, Dr.
Outcome results
None listed