Construction of a Cohort for Pan-Vascular Disease Among Employees of Taizhou People's Hospital

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06545799

Enrollment

1000

Registered

2024-08-09

Start date

2024-09-01

Completion date

2034-09-01

Last updated

2024-08-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Death, Myocardial Infarction, Stroke

Brief summary

1. Participant Recruitment During the annual health check-ups for hospital staff, potential participants are recruited. Those who express interest are provided with a detailed explanation of the study's objectives, content, and procedures, and are required to sign an informed consent form. 2. Screening Phase Medical history is collected, including any previous occurrences of myocardial infarction, ischemic or hemorrhagic stroke, or history of coronary, carotid, or peripheral arterial revascularization. 3. Baseline Data Collection 1\. Health Questionnaire Survey: Collect demographic information, medical history, and data on nutrition, physical activity, and smoking habits through a questionnaire. 2\. Clinical Assessments: Conduct the following assessments for all enrolled participants: * High-sensitivity cardiac troponin I and NT-proBNP testing * Non-invasive arterial stiffness testing * Measurement of visceral and subcutaneous fat content * Fundus photography * Body composition analysis 4 Regular Follow-Up Annual follow-up for a total of 10 years. The follow-up includes: 1. . Collection of updated demographic information and medical history, as well as repeated questionnaires on nutrition, physical activity, and smoking habits. 2. . Reassessment of the following items: * High-sensitivity cardiac troponin I and NT-proBNP testing * Non-invasive arterial stiffness testing * Measurement of visceral and subcutaneous fat content * Fundus photography * Body composition analysis 5 Outcome Evaluation 1）. Primary Outcomes: Cardiovascular mortality, non-fatal myocardial infarction, or non-fatal stroke events. 2）. Secondary Outcomes: All vascular events, changes in cardiovascular biomarkers, and degree of arterial stiffness.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

45 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

1. Employed or retired individuals aged 45 years or older; 2. Willing to sign an informed consent form and voluntarily participate in health examinations and related data collection.

Exclusion criteria

1. History of myocardial infarction, ischemic or hemorrhagic stroke, or revascularization of coronary, carotid, or peripheral arteries; 2. Employees with severe psychological disorders who are unable to cooperate with the study; 3. Pregnant or breastfeeding women.

Design outcomes

Primary

Measure	Time frame	Description
Cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke events	September 2024 to August 2034	Cardiovascular death: Death from heart or blood vessel diseases. Non-fatal myocardial infarction: Heart attack that does not result in death. Non-fatal stroke events: Stroke incidents that do not result in death.

Contacts

Primary ContactQingqing Zhang

18061986120@189.cn+86 180 6198 6120

Outcome results