Performance of Mid-Upper Arm Circumference for Detection of Severe Acute Malnutrition in Indonesian Under-Fives

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06545240

Enrollment

421

Registered

2024-08-09

Start date

2020-01-01

Completion date

2020-02-29

Last updated

2024-08-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe Acute Malnutrition

Keywords

mid-upper arm circumference, sensitivity, severe acute malnutrition, specificity, WHZ index

Brief summary

WHO recommends 11.5 cm as a cut-off point of Mid-Upper Arm Circumference (MUAC) to detect and/or diagnose severe acute malnutrition (SAM) in under-five. MUAC is practical and useful, especially in area with limited facilities which has no standardized scale and infantometer. However, several studies showed that this cut-off need to be evaluated as it has modest detection rate for SAM. This study aims to evaluate diagnostic value of MUAC with 11.5 cm cut-off compared to WHZ as gold standard to identify SAM. The sensitivity, specificity, positive and negative predictive value of MUAC with 11.5 cm as a standard cut-off will be evaluated. This study also aim to find new cut-off value that may offer better diagnostic performance. The main research questions were: What is the diagnostic accuracy of Mid-Upper Arm Circumference (MUAC) compared to the Weight for Height Z Score (WHZ) in identifying SAM in children, and what is the optimal MUAC cut-off value for enhanced diagnostic performance?

Interventions

DIAGNOSTIC_TESTMid-upper arm circumference

Mid-upper arm circumference was taken using non-stretchable band SECA 202

Study design

Observational model

ECOLOGIC_OR_COMMUNITY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

6 Months to 59 Months

Healthy volunteers

Yes

Inclusion criteria

* under-fives that 6-59 months-old

Exclusion criteria

* ascites * edema * hydrocephalus * tumor or oncologic diseases * organomegaly * uncooperative during measurement

Design outcomes

Primary

Measure	Time frame	Description
Diagnostic value of MUAC in diagnosing SAM compare to WHZ-index	2 months	To evaluate sensitivity, specificity, positive and negative predictive value of MUAC

Secondary

Measure	Time frame	Description
Finding new cut off value that offer better diagnostic performance using ROC	2 months	To compare sensitivity, specificity, positive and negative predictive value of MUAC with 11.5 cm as standard cut off and to new cut-off value that may offer better diagnostic performance

Countries

Indonesia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026