Clinical Course
Conditions
Brief summary
Abstract: Studies demonstrate that the use of nutritional supplements containing beta-glucans stimulates the immune system, modulates inflammatory activity, and promotes so-called immune training. Beta-glucans are prebiotics that stimulate the growth and activity of gastrointestinal microbiota and inhibit pathogen growth. Nutritional intervention is crucial for patients' positive evolution, and providing a supplement with highly bioavailable nutrients can make a difference in their nutritional, metabolic, and immune status. Therefore, the study aims to verify the effectiveness of the innate and adaptive immune response to a nutritionally balanced fermented food, containing oral or enteral beta-glucans, in patients treated at 3 Emergency Care Units in São José do Rio Preto, São Paulo, Brazil. This is a prospective randomized study with a characteristic design involving patients treated in the medical wards of 3 Emergency Care Unit. The following assessments will be conducted: Global Subjective Assessment for adults and Mini Nutritional Assessment for the elderly, Sociodemographic, and Laboratory Evaluation.
Interventions
DIETARY_SUPPLEMENTBioNutri AR-1,
intervention with fermented and nutritionally balanced food twice a day
Sponsors
Kaiser Clinic and Hospital
Federal University of São Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
Patients admitted to the medical clinic ward
Exclusion criteria
Patients unable to swallow
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| length of hospital stay | during hospitalization |
Secondary
| Measure | Time frame |
|---|---|
| need for readmission | up to 24 weeks |
| need for ICU | up to 24 weeks |
Contacts
Primary ContactFERNANDO SABIA TALLO, PhD
Outcome results
None listed