Early Pregnancy Ultrasound Measurements and Prediction of First Trimester Pregnancy Loss.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06540092

Enrollment

126

Registered

2024-08-06

Start date

2024-03-19

Completion date

2024-07-30

Last updated

2024-08-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

First Trimester Abortion

Keywords

ultrasound measurments

Brief summary

Ultrasound measurements of fetus during first trimester may be an indicator of first trimester pregnancy loss. Investigators took 4 measurements of the fetus on 2 intervals during first trimester to confirm this hypothesis.

Detailed description

Ultrasound examination of gestational sac (GS) diameter, yolk sac (YS) diameter, crown rump length (CRL) diameter, embryonal heart rate (HR) using Samsung Medison SonoAce R3 through transvaginal probes (6.5 MHz) was conducted on 126 pregnant women. At least 2 scans were done for each participant one between 6-8 weeks and another one by the end of first trimester. Results then were compared to get the cut off values that can predict pregnancy loss.

Interventions

DIAGNOSTIC_TESTultrasound

ultrasound measurements during first trimester

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* • Healthy pregnant female patient in the reproductive age group; 18 - 40 years old. * Gestational age: 6 - 13 weeks of gestations. * Singlton or multifetal pregnancy. * Any mode of conception included spontaneous, after superovulation with clomiphene citrate or letrozole with, or without, intrauterine insemination (IUI), and in vitro fertilization (IVF) after superovulation with gonadotropins.

Exclusion criteria

* • Patient with unsure date for the last menstrual period. * Pregnant women above 13 weeks gestation. * Patient with symptoms of threatened abortion or ectopic pregnancy at the initial antenatal visit. * Patient unable to come for follow up. * Any medical disorders as DM, HTN, …

Design outcomes

Primary

Measure	Time frame	Description
The relation between early pregnancy ultrasound measurements (GSD, YSD, CRL, HR), viability, and continuation of pregnancy till 13 weeks of gestation.	6-7 weeks	2 measures of the fetus were obtained and compared to get first trimester pregnancy outcome

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026