DVT
Conditions
Brief summary
Hospitalized patients are at high risk of venous thromboembolism (VTE), and the appropriate use of thromboprophylaxis can significantly reduce the incidence of VTE in high-risk patients. We investigated the pattern of VTE prophylaxis administration among elderly medical patients and assessed its appropriateness based on the American College of Chest Physicians (ACCP) recommendations. Methods A cross-sectional single-center study will be conducted between July 2024 and December 2024, including hospitalized (\> 48 h), (≥ 60 years), medical and surgical patients, and excluding patients receiving anticoagulant for other reason, having contraindication to thromboprophylaxis, or had VTE diagnosed within 48 h. The Padua and caprine prediction scores will be used to determine the patients' risk for VTE, and thromboprophylaxis use will be assessed against the ACCP recommendations.
Interventions
OTHERDVT prophyllaxis
VTE prophylaxis administration among patients based on the American College of Chest Physicians (ACCP) recommendations
Sponsors
Egyptian Chinese University
Teachers Hospital
Ain Shams University
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patient records * admitted to the ICU with * medical or surgical causes * recieved anticoagulants for DVT prophylaxis
Exclusion criteria
* Patients already on anticoagulant therapy, * had history of previous DVT, * had End-stage liver disease, * admitted with hemorrhage/bleeding * not prescribed DVT prophylaxis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Padua score for medical patients | within 24 hours of ICU admission | Venous thromboembolism Risk assessment (Scores 0-3 are low risk and do not warrant prophylaxis. Scores ≥4 are high risk for VTE and subsequent complications; recommendation for thromboprophylaxis.) |
| Caprini score for surgical patients | within 24 hours of ICU admission | Venous thromboembolism Risk assessment (Total score of 0-1: Low risk of VTE Total score of ≥3: High/moderate risk of VTE ) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Bleeding risk assessment | within 24 hours of ICU admission | — |
| Direct Anticoagulant cost | within 24 hours of ICU admission till ICU discharge(at least 48 hours) | sum of costs related to the anticoagulant administration for DVT Prophylaxis |
| Adverse drug reaction cost | within 24 hours of ICU admission till ICU discharge (at least 48 hours) | sum of costs related to the Adverse drug reaction for DVT Prophylaxis |
Countries
Egypt
Outcome results
None listed