Emergence Agitation
Conditions
Brief summary
The primary aim of the study was to test the hypothesis that remifentanil administered for analgesia prevents emergence agitation more effectively than fentanyl and N2O in patients undergoing rhinoplasty who received desflurane as an inhaled anesthetic agent. The secondary aim of the study was to compare the demographic data, intraoperative and postoperative hemodynamic data, surgical time and modified Aldrete score of patients who received different intraoperative analgesia methods.
Interventions
DRUGRemifentanil
remifentanil infusion
DRUGN2O
Use of N2O for analgesia
DRUGFentanyl
Use of Fentanylfor analgesia
Sponsors
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
The study included patients over the age of 18, planned to undergo rhinoplasty by the plastic and reconstructive surgery department, and American Society of Anesthesiologist (ASA) I-II. \-
Exclusion criteria
* Patients with a known history of allergy to the drugs to be administered in the study, ASA III and above, body mass index (BMI) 35\>kg/m2, younger than 18 years of age, any problems that would prevent general anesthesia in the preoperative evaluation (upper respiratory tract infection, etc.), and those who did not agree to participate in the study were excluded from the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Richmond Agitation-Sedation Scale (RASS) | Postoperative care unit 1.second_5. second_15.second | * 4 Combative, violent, danger to staff * 3 Pulls or removes tube(s) or catheters; aggressive * 2 Frequent non-purposeful movement, fights ventilator * 1 Anxious, apprehensive, but not aggressive 0 Alert and calm * 1 Awakens to voice (eye opening/contact) \> 10 seconds * 2 Light sedation; briefly awakens to voice (eye opening/contant) \< 10 seconds * 3 Moderate sedation; movement or eye opening. No eye contact * 4 Deep sedation; no response to voice, but movement or eye opening to physical stimulation * 5 Unarousable; no response to voice or physical stimulation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Heart rate | Before induction ,After intubation 1 min,After intubation 5 min, After intubation 15 min After intubation 30 min | beats/min |
| mean arterial pressure | Before induction ,After intubation 1 min,After intubation 5 min, After intubation 15 min After intubation 30 min | mmHg |
Countries
Turkey (Türkiye)
Contacts
Primary ContactHülya Tosun Söner
Backup ContactOsman Uzundere
Outcome results
None listed