Cardiometabolic Syndrome, Enjoyment, Exercise Overtraining, Obesity
Conditions
Keywords
interval training, obesity, overweight, childhood, cardiometabolic risk, enjoyement, lipidomics, body composition, physical fitness
Brief summary
The main purpose of this study is to compare the impact of 12-week moderate-intensity interval training (MIIT) versus combined MIIT with high-intensity interval training (HIIT) on physical fitness, cardio metabolic, lipidomic, hematological and psychological characteristics in young overweight/obese girls.
Interventions
OTHERMIIT
12-week supervised exercise program consisting of moderate-intensity interval training (MIIT) MIIT: 3 series of 4-8 repetitions of 30-s of work at 70-75% of MAS and 30-s of active recovery at 50% of MAS. 3 exercise sessions per week. Additionally, participants receive no individualized nutritional counseling.
OTHERMIIT + HIIT
12-week supervised exercise program consisting of moderate-intensity interval training (MIIT) (6-week) and high-intensity interval training (HIIT) (6-week). MIIT: 3 series of 4-8 repetitions of 30-s of work at 70-75% of MAS and 30-s of active recovery at 50% of MAS. HIIT: 3 series of 5 repetitions of 30-s of work at 100% of MAS and 30-s of active recovery at 50% of MAS for weeks 7-9, as well as two series of 10 repetitions of 30-s of work at 100% of MAS and 30-s of active recovery at 50% of MAS for weeks 10-12. 3 exercise sessions per week. Additionally, participants receive no individualized nutritional counseling.
OTHERControl group
Habitual physical activity No additional physical intervention Additionally, participants receive no individualized nutritional counseling.
Sponsors
Association Tunisienne d'Etude & de Recherche sur l'Athérosclérose
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
12 Years to 15 Years
Healthy volunteers
No
Inclusion criteria
* Female gender, * Overweight or obese according to the BMI classification, * Age, 12 to 15 years, * Personal or parental/guardian written consent
Exclusion criteria
* Severe infectious or inflammatory diseases, * Irregular menstrual cycles * Participation in organized exercise training in the last 6 months or additional physical - * recreational activities, except physical education classes. * Using medications, hormone therapy or dietary supplements
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in body mass index (BMI) | 12 weeks | measures of weight in kilograms, height in meters, calculation of BMI in kg/m\^2) |
| Changes in plasma triglycerides | 12 weeks | will be assessed using an Alinity-Abbott autoanalyzer |
| Enjoyment | 6 and 12 weeks | Enjoyment will be measured using the validated Physical Activity Enjoyment Scale. This scale was used to assess the level of enjoyment following interventions using the participants' responses to 18 items rated on a 7-point bipolar rating scale. The assessment consists of questions relateding to the enjoyment after intervention with the instruction, Please rate how you feel about the physical activity you have been doing at the moment about the physical activity you have been doing. An overallOverall enjoyment of physical activity score was generated by summing the individual item scores. Scores ranged from 18-126, with higher scores reflecting higher levels of enjoyment. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Heart rate | 12 weeks | Heart rate will be recorded using a heart rate monitor (S810, Polar, Kempele, Finland) during the incremental running test the Spartacus test. |
| Changes in Aerobic velocity | 6 and 12 weeks | Aerobic velocity will be measured with incremental running test the Spartacus test. This test is validated for the evaluation of aerobic capacity for obese adolescents. A rectangle of 750 m (75 × 10 m) will be created with different marks set at regular intervals, which represent the different speeds (from 7 to 18 km/h). Each stage lasts three minutes whereby the first stage is set at 7 km/h and each following stage increasing by 1 km/h. During each stage, the participant had 15 s to reach the corresponding mark and then 15 s of rest. Participants adjusted their running speed simultaneously to cones and audio beep. The test ended when the subject was no longer able to maintain the pace for two consecutive occasions or when he decided to stop due to exhaustion. |
| Change in sprint performance | 12 weeks | Sprinting performance will be evaluated by 10-m, 20-m, 30 --m and 60-m sprints, using a series of paired photocells with an accuracy of 0.01 s (Brower Timing System, Salt Lake City, UT). |
| Changes in lipidomic profile | 12 weeks | Lipidomic profile will be assessed by measuring selected plasma polyunsaturated fatty acids (PUFAs), oxylipins and endocabnnabinnoids by LC-MS/MS method |
| Changes in hematological parameters | 12 weeks | Hematological parameters included red blood cell count, hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, leukocyte count , neutrophil count , lymphocyte count, monocyte count , eosinophil count and platelet count will be measured using an automated cell counter (Sysmex XN450; Norderstedt, Germany). |
Countries
Tunisia
Contacts
Primary ContactAmani Kallel, PhD
Backup ContactMoncef Feki, MD
Outcome results
None listed