Cutaneous Squamous Cell Carcinoma
Conditions
Keywords
B-catenin, Cutaneous squamous cell carcinoma, Immunohistochemistry
Brief summary
Examine the role of B-catenin in differentiation of cutaneous squamous cell carcinoma from other lesions that may be similar to it
Detailed description
Skin cancer is one of the most common form of cancer worldwide. Cutaneous squamous cell carcinoma is one of most common skin tumers that caused by many factors as ultra violet ,ionizing radiation and others . It was an advanced spectrum ranging from actinic keratosis to invasive and metastatic squmous cell carcinoma. Correct identification of cutaneous squamous cell carcinoma is a challenge as it has both clinically and histopathologically mimickers. So the aim of this study is to identify the expression of B-catenin in cutaneous Squamous cell carcinoma and its mimickers.
Interventions
BIOLOGICALImmunohistochemical staining
Staining of cutanous squamous cell carcinoma and its mimickers by monoclonal antibodies against human B-catenin by immunohistochemical procedures
Sponsors
Sohag University
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* tissue blocks with sufficient materials Cases with sufficient data
Exclusion criteria
* tissue blocks with insufficient and necrotic materials. Casas with insufficient data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Detection of B-catenin expression in cutanous squamous cell carcinoma and its mimickers | 6 month | Detection of expression of B-catenin in cutaneous squamous cell carcinoma and its mimickers by immunohistochemical procedures using antihuman B-catenin monoclonal antibodies |
Countries
Egypt
Contacts
Primary ContactNermeen S Habeeb, Doctor
Outcome results
None listed