Decompression of Odontogenic Cysts

The Effect of Decompression on Histologic Diagnoses of Cystic Jaw Lesions

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06536907

Enrollment

Registered

2024-08-05

Start date

2015-01-01

Completion date

2023-09-01

Last updated

2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cysts Dental, Keratocysts of the Jaw, Odontogenic Cysts, Pathology

Keywords

biopsy, diagnosis, keratocysts, odontogenic cysts, oral pathology, surgical decompression

Brief summary

The aim of this case-control study is to evaluate the effects of decompression of cystic jaw lesions by means of comparing pre- and post-decompression histologic findings. The main question it aims to answer is: Does decompression of cystic jaw lesions alter the histologic diagnosis? A retrospective analysis was performed based on the comparison of initial and final histologic diagnoses of patients with an odontogenic cystic lesion, that was surgically treated with decompression followed by a definitive surgery.

Detailed description

The study included patients with a histologic diagnosis of an odontogenic cystic lesion, that was surgically treated with decompression followed by a definitive surgery. The study was carried out retrospectively by means of evaluating records, surgical and histologic reports of patients. Pre- and post-decompression histologic findings were compared in effort to understand if decompression leads to alteration in histologic character and change in diagnoses of lesions.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* To have an initial diagnosis of an odontogenic cystic jaw lesion confirmed with an incisional biopsy. * The patients must have undergone decompression and, enucleation or enucleation and peripheral ostectomy after decompression period.

Exclusion criteria

* Previously treated patients * The patients with missing information in medical and/or dental records * The patients who did not adhere to follow-up protocol

Design outcomes

Primary

Measure	Time frame	Description
Change in histologic diagnosis following decompression (yes/no)	A decompression period ranging between 2 and 15 months	A comparison will be made between the initial histologic diagnosis and post-decompression definitive histologic diagnosis of the cystic jaw lesions

Countries

Turkey (Türkiye)

Outcome results