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The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study

The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06535867
Enrollment
5122
Registered
2024-08-02
Start date
2024-07-30
Completion date
2031-07-30
Last updated
2026-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol Drinking, Betel Chewer's Mucosa, Smokeless Tobacco Hyperkeratosis, Smoking, Smoking, Cigarette, Smoking, Tobacco, Tobacco Smoking, Tobacco Use

Keywords

smoking, smoking, cigarette, smoking, tobacco, smokeless tobacco, betel leaf, areca nut, paan masala, alcohol use, Memorial Sloan Kettering Cancer Center, 24-148

Brief summary

Mobile health (mHealth) will be used for early detection of oral cancer and pre-cancer lesions, and to improve awareness of oral cancer among the population and knowledge of oral cancer diagnosis among frontline health providers. This program is inclusive of long term surveillance to downstage oral cancer in India

Interventions

DIAGNOSTIC_TESTmHealth

The mobile health (mHealth) program will be used for early detection of oral cancer and pre-cancer lesions, and to improve awareness of oral cancer among the population and knowledge of oral cancer diagnosis among frontline health providers.

Sponsors

Memorial Sloan Kettering Cancer Center
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Positive for any one or more of the following: * All individuals aged above 18 years positive for habits (smoking and smokeless tobacco, chewing betel leaf, areca nut, paan masala, and/or regular use of alcohol) * Clinical signs/symptoms (non-healing ulcers, white/ red/red \& white patches in the mouth, restriction of mouth opening and swelling of the neck) * All individuals aged above 40 irrespective of habit/oral lesions

Exclusion criteria

* Individuals already diagnosed with oral cancer and undergoing treatment for oral cancer * Under treatment for tuberculosis or suffering from any acute illness/ debilitating systemic disorders

Design outcomes

Primary

MeasureTime frameDescription
Comparison of mHealth with conventional oral cancer screeningUp to 5 yearsTo compare the efficacy of conventional screening with mHealth in identification of oral potentially malignant disorders (OPMDs) / oral cancer.

Countries

United States

Contacts

CONTACTMilind Rajadhyaksha, PhD
rajadhym@mskcc.org646-608-2364
CONTACTAditi Sahu
sahua@mskcc.org646-608-1935
PRINCIPAL_INVESTIGATORMilind Rajadhyaksha, PhD

Memorial Sloan Kettering Cancer Center

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 23, 2026