Anorexia Nervosa, Binge Eating/Purging Type, Barrett Esophagus, Eating Disorders, Esophageal Adenocarcinoma, Rumination, Vomiting
Conditions
Brief summary
To better define the presence of Barrett's esophagus (BE) via non-endoscopic testing in an eating disorder cohort with purging (vomiting/rumination) behaviors
Detailed description
A prospective cohort study to assess the presence of BE in those with purging behaviors from their eating disorders has not been completed. There are multiple case reports describing a younger population not meeting typical screening guidelines whom developed this condition. To better define the presence of Barrett's esophagus (BE) via non-endoscopic testing in an eating disorder cohort with purging (vomiting/rumination) behaviors. Individuals with severe forms of eating disorders with purging and ruminating behaviors not meeting the current screening guidelines for BE will still test positive for BE.
Interventions
DEVICEEsoGuard
device used to collect esophageal cell samples to test for the presence of abnormal cells which may indicate a dx of Barrett's esophagitis.
Sponsors
Lucid Diagnostics, Inc.
Denver Health and Hospital Authority
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patients diagnosed with an eating disorder diagnosis that includes purging history * Ages 18-65 * Purging history =\>5 years * Purging or rumination at a minimum of once daily upon admission. * Admission to the ACUTE Center for Eating Disorders and Severe Malnutrition
Exclusion criteria
* Any eating disorder diagnosis that does not include purging behaviors * Ages under 18 and over 65 * Patients who otherwise meet the current ACG screening guidelines (chronic GERD and 3 or more risk factors for Barrett's mentioned in the Background) * Received mandated care at time of enrollment * Inability to consent to participate in the research
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of patients positive for BE | 12 months | Individuals with severe forms of eating disorders with purging and ruminating behaviors not meeting a current screening guidelines for BE will test positive for BE |
Countries
United States
Contacts
Primary ContactMarina J Foster, BA
Backup ContactAllison Nitsch, MD
Outcome results
None listed