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Clinical Retrospective Study Analysis of Postoperative Complications Following Hepatectomy

Clinical Retrospective Study Analysis of Postoperative Complications Following Hepatectomy

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06532214
Enrollment
2000
Registered
2024-08-01
Start date
2024-01-01
Completion date
2025-12-31
Last updated
2024-08-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Dysfunction, Liver Failure

Keywords

hepatectomy, liver failure, Post-hepatectomy liver failure

Brief summary

Hepatectomy is a crucial surgical method for treating liver diseases such as liver cancer, hepatic hemangiomas, and biliary stones. Although hepatectomy has achieved significant therapeutic effects, postoperative complications remain an inevitable issue. Complications following hepatectomy include liver failure, hepatic vascular thrombosis, wound infection at the hepatic incision, and bile leakage, among others. These complications pose a serious threat to patients' health and life, and also increase the waste of medical resources and the cost of treatment. Currently, research on postoperative complications of hepatectomy mainly focuses on small sample studies from a single center, and most studies only focus on a specific complication, lacking comprehensive and systematic analysis. Therefore, it is necessary to conduct a retrospective study analysis of complications related to hepatectomy to more comprehensively and objectively understand the incidence, risk factors, prevention, and treatment of postoperative complications, providing clinical doctors with more scientific treatment plans and guidance.

Interventions

DIAGNOSTIC_TESTInternational Study Group for Liver Surgery (ISGLS)

According to the ISGLS criteria, the patient was judged to have liver failure and further analysis

Sponsors

Nanfang Hospital, Southern Medical University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years

Inclusion criteria

* 1\. Patients aged 18-80 years 2.Patients who underwent liver resection surgery at the participating centers

Exclusion criteria

*

Design outcomes

Primary

MeasureTime frameDescription
Post-hepatectomy liver failure (PHLF)On and after the 5th postoperative dayPHLF is commonly diagnosed and classified according to the criteria of the International Study Group for Liver Surgery (ISGLS), utilizing markers of liver function measured on or after postoperative day 5 (POD5).

Secondary

MeasureTime frameDescription
mortalityDuring 30 days after surgeryThe patient died postoperatively

Countries

China

Contacts

Primary ContactKai Wang
kaiwang@smu.edu.cn13710574386

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 5, 2026