Healing Surgical Wounds, High Risk Pregnancy
Conditions
Keywords
amniotic fluid, cesarean section scar (healing)
Brief summary
The goal of this randomized controlled trial is to investigate the effect of injection of autologous amniotic fluid in the healing of the scar of cesarean section among high-risk population. Investigator's aim is to know : quality of wound healing, rate of infection and time needed for complete healing. Participants will be divided into two groups. All participants will undergo cesarean section. We will inject autologous amniotic fluid in the edges of the wound during skin closure in half of the participants. Wound healing will be assessed at 1st, 2nd and 6th week postoperatively.
Detailed description
After surgery, participants will be observed along 6 weeks (at 1, 2 and 6 weeks intervals) and scars will be assessed regarding color, thickness, pliability and presence of exudate.
Interventions
BIOLOGICALautologous amniotic fluid
10 cc of amniotic fluid aspirated after opening uterine incision in cesarean section, then Injected in edges of skin before closure
OTHERNo amniotic fluid injected in skin edges
conventional closure of skin
Sponsors
Kasr El Aini Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
30 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Age \> 30 years old. * Anemic patients * Maternal chronic disease e.g., Diabetes and Hypertension * BMI of \> 25 Kg/m2. * Underwent previous CS.
Exclusion criteria
* Rupture of membrane. * No previous section. * Anhydraminos. * Congenital malformation of the fetus.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Quality of wound healing | 1,2,6 weeks postoperative | Scars will be assessed objectively regarding Color, Thickness, Pliability, Exudate in participants and controls |
Countries
Egypt
Outcome results
None listed