Elderly Patients Undergoing Elective Non-cardiac Surgery
Conditions
Keywords
hypotension, general anesthesia, inferior vena cava
Brief summary
Based on the preoperative ultrasound detection of various parametric indicators of the inferior vena cava cross-section, including the ratio of the inferior vena cava's long and short axes, cross-sectional area and circumference during two-dimensional and three-dimensional imaging, as well as the changes in respiratory variability of each parameter, we explored the predictive value of IVC ultrasound indicator parameters on hypotension after induction of general anesthesia in elderly patients undergoing elective non-cardiac surgery, screened the sensitive indicators, and calculated the cut-off values.
Interventions
DIAGNOSTIC_TESTMultidimensional ultrasound of the inferior vena cava
Cross-sectional parameters of the inferior vena cava include two-dimensional longitudinal diameter, cross-sectional length and short diameter, circumference, and cross-sectional area, as well as cross-sectional length and short diameter, circumference, and cross-sectional area in three-dimensional imaging
Sponsors
Zhuan Zhang
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Elderly patients undergoing elective non-cardiac surgery under general anesthesia; * Age 65-85 years old; * Body mass index (BMI) 18-28 kg/m2; * American society of anesthesiologists (ASA) class I-III.
Exclusion criteria
* Patient refusal or lack of cooperation; * Inability to communicate properly; * Severe sinus bradycardia, pacemaker implantation, atrioventricular block, and atrial fibrillation; * Presence of severe hepatic and renal function abnormalities; * Preoperative cardiac ultrasound suggesting LVEF \<50%; * Tricuspid valve displacement \<16 mm by preoperative cardiac ultrasound; * Chronic obstructive pulmonary disease; * Pulmonary hypertension; * Administration of drugs that inhibit the renin-angiotensin-aldosterone system; * Possibility of a difficult airway.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in the level of Mean Arterial Pressure | Baseline (before induction), 10 min after induction | The outcome above should be measured at the time before induction, 1 min after induction, 2 min after induction, 3 min after induction, 4 min after induction, 5 min after induction,10 min after induction |
| Changes in the level of Systolic Blood Pressure | Baseline (before induction), 10 min after induction | The outcome above should be measured at the time before induction, 1 min after induction, 2 min after induction, 3 min after induction, 4 min after induction, 5 min after induction,10 min after induction |
| Multidimensional ultrasound of the inferior vena cava | Baseline (before induction) | The outcome above should be measured at the time before induction |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes in the level of Heart Rate | Baseline (before induction), 10 min after induction | The outcome above should be measured at the time before induction, 1 min after induction, 2 min after induction, 3 min after induction, 4 min after induction, 5 min after induction,10 min after induction |
| Changes in the level of Diastolic Blood Pressure | Baseline (before induction), 10 min after induction | The outcome above should be measured at the time before induction, 1 min after induction, 2 min after induction, 3 min after induction, 4 min after induction, 5 min after induction,10 min after induction |
Countries
China
Contacts
Primary Contactzhuan zhang, professor
Outcome results
None listed