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Enhanced Community First Responder System Evaluation in Singapore

Evaluation of an Enhanced Community First Responder Support System to Improve Bystander Cardiopulmonary Resuscitation Quality for Patients Experiencing Out-of-hospital Cardiac Arrest

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06530433
Acronym
TCPR-Link
Enrollment
165
Registered
2024-07-31
Start date
2024-08-01
Completion date
2028-12-31
Last updated
2026-04-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Out-Of-Hospital Cardiac Arrest

Keywords

cardiopulmonary resuscitation, Bystander CPR, Community first responder, CPRCard, TCPR Link

Brief summary

The rise in out-of-hospital cardiac arrest (OHCA) cases in Singapore highlights the need for effective bystander cardiopulmonary resuscitation (BCPR). Despite many lay responders performing CPR, survival rates with good neurological outcomes have not significantly improved, prompting research into the quality of CPR as a critical factor. The study by Gallagher EJ et al. showed a significant survival improvement with high-quality CPR. To address this, the Unit of Pre-hospital and Emergency Research (UPEC) trained thousands of community first responders (CFRs) in simplified CPR techniques using hands-only and DA-CPR methods. A significant innovation is the CPRcard®, developed by Laerdal in Norway, which offers real-time feedback on the quality of chest compressions. However, only 36% of CFRs using the CPRcard® achieved the desired compression standards, indicating room for improvement. The study proposes enhancing CFR support with information communication technology (ICT), enabling two-way audio and one-way video communication between CFRs and dispatchers. This aims to reduce stress among responders, increase their willingness to engage with OHCA alerts, and improve CPR quality. The clinical trial in Singapore will compare the current system against the enhanced CFR support system (eCSS), focusing on the real-time relay of CPR performance data, communication ease, and implementation factors. The high-quality CFR and OHCA registries in Singapore provide a robust setting for this research, aiming to enhance CPR delivery and improve OHCA outcomes through technology and real-time support.

Interventions

DEVICECPRCard + TCPR Link App and Web

Application that allows responder to perform CPR with two-way audio communication and one-way video streaming to SCDF Dispatcher

DEVICECPRCard Only

Control arm with standard care of procedure that Bystander using CPRCard only

Sponsors

Singapore General Hospital
Lead SponsorOTHER
Duke-NUS Graduate Medical School
CollaboratorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Masking description

Not possible to mask participants and care provider. Outcome is assessed by a device. Analyst will be masked.

Intervention model description

This Health Services research intervention will evaluate effect of live CPR video CPR performance of the volunteer to call-taker in improving CPR Quality and clinical outcomes among the OHCA patients.

Eligibility

Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* 18 years old and above * SCDF registered CFRs * Trial dispatchers with an active account of myResponder® app on their mobile phones

Exclusion criteria

* The CFRs who are pregnant * Experiencing any serious physical Conditions * Mental Health Conditions

Design outcomes

Primary

MeasureTime frameDescription
Good Chest Compression Depth (4-6cm)Throughout chest compression before handing over to EMS (up to 24 hours)OHCA events achieving great proportions of adequate compressions (achieving depth within the target range of 4-6 cm)

Secondary

MeasureTime frameDescription
Survivor discharging rateThroughout Hospital Admission (up to 1 year)Return of spontaneous circulation (ROSC) at scene or at emergency department; survival to discharge; neurologically intact survival

Countries

Singapore

Contacts

CONTACTFahad J Siddiqui, MSc
fahad.siddiqui@duke-nus.edu.sg+6566017951
CONTACTAlexander A White, MSc
alexander.elgin.white@upec.sg+65 90674081

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 14, 2026