Intrabony Periodontal Defect
Conditions
Brief summary
Research is to compare and evaluate the clinical and radiographic outcomes of the enamel matrix derivative with or without connective tissue wall graft for noncontained infrabony defects using simplified papilla preservation technique .
Detailed description
Research is to compare and evaluate the clinical and radiographic outcomes of the enamel matrix derivative with or without connective tissue wall graft for noncontained infrabony defects using simplified papilla preservation technique .The objectives is to assess the probing pocket depth reduction, clinical attachment level gain,gingival recession depth and radiographic bone gain. The TEST group will be treated withSIMPLIFIED PAPILLA PRESERVATION flap with connective tissue graft and enamel matrix derivative and the CONTROL group will be treated with SIMPLIFIED APILLA PRESERVATION flap and enamel matrix derivative. The total number of participants included will be 30 (Control-15; Study-15) with a 6 month follow up.
Interventions
PROCEDUREEnamel matrix derivative
connective tissue graft and Enamel matrix derivative in the defect area
Sponsors
Krishnadevaraya College of Dental Sciences & Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients willing to participate in the study. * Participants aged ≥18 years to 55 years. * Presented with non contained infra bony defects. * Presence of at least 1 non contained infra bony defect(IBD) with a pocket probing depth ≥6mm after reevaluation of the hygienic phase and a depth of IBD ≥3mm as detected on radiographs, with radiographic angulation of ≥37⸰ , and exhibiting a 1 or 2 wall infra bony defect15(assessed by a bone sounding and confirmed intrasurgically) * Patient's full mouth plaque score and bleeding score \<20% at the time of surgical procedure. * No history of periodontal surgery at the experimental site.
Exclusion criteria
* Grade III mobility, endodontically treated teeth. * Pregnant and lactating females. * History of tobacco smoking . * Patients with systemic disease. * Known allergy or hypersensitivity to EMD. * Presence of pulpal and peri apical involvement
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| clinical attachment gain | 6 months | change in attachment level for patient with isolated 2 or 3 wall defect treated with enamel matrix derivative and connective tissue wall graft in 1,3 and 6 months follow up |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| pocket probing depth | 6 months | change in pocket probing depth from baseline to 1,3 and 6 months |
| radiographic bone gain | 6 months | change in radiographic bone level from baseline to 1,3,6 months |
| recession reduction | 6 months | change in recession from baseline to 1,3 and 6 months |
| plaque index | 6 months | change in plaque index from baseline to 1,3 and 6 months |
| gingival index | 6 months | change in calculus index from baseline to 1,3 and 6 months |
Contacts
Primary ContactPrabhuji MLV, MDS
Backup ContactHead of the department and professor
Outcome results
None listed