COPD, PAD
Conditions
Brief summary
The aim of this study To show the effect of breather on ventilatory and vascular function in COPD patient with intermittent claudication.
Detailed description
recent researches show that COPD patients have risk of developing peripheral arterial disease (PAD) which represented on patient by intermittent claudication inspiratory muscle trainer as the breather device show increasing in inspiratory muscle strength and endurance; reduction of dyspnea; and improving of exercise tolerance . Because of all this things this study tends to show the effect of the breather on ventilatory and vascular function in COPD patient with intermittent claudication.
Interventions
DEVICEThe BREATHER
The BREATHER is Light/Medium resistance inspiratory muscle trainer which has significance role in increasing inspiratory muscle strength and endurance which could result in a decreased sensation of dyspnea
patient will receive the usually pharmacological treatment.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
50 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* sixty male patients with diagnosed with grade I and grade II COPD their ages ranged between 55-60years * All patients will be clinically and medically stable when attending the study. * Body mass index (BMI) is 18.5 to 24.9 kg/m2. * History of unilateral exertional leg pain, * Ambulation during a graded treadmill test limited by leg pain consistent with intermittent claudication (stage II of the fontaine classification of pad), * And an ankle-brachial index (ABI) of 0.90 or lower at rest or 0.73 or lower after exercise.
Exclusion criteria
* cardiovascular insufficiency, * Recent myocardial infarction, * heart failure, * arrhythmia, * DVT, * Intracranial hypertension, * Pneumonia, * kidney failure, * fractures, * uncooperative patients, * cognitive impairment preventing a patient from participation in exercises.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Ventilatory function: by spirometry test | 4 weeks | Spirometry is a physiological test that measures the ability to inhale and exhale air relative to time. |
| Vascular function: by doppler ultrasound | 4 weeks | Doppler ultrasound is a simple and non-invasive and method for the evaluation of early atherosclerosis. It can be used as a screening program for PAD in populations with high risk for atherosclerosis. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Functional capacity assessment: by 5 repetitions sit to stand test (5R-STS) | 4 weeks | (5R-STS) test is an objective test of functional impairment commonly used in various diseases including COPD which is used to measure the severity of disease and to monitor recovery. |
| Treadmill exercise testing | 4 weeks | The results of the tests will be expressed in units of distance that will be walked up to the claudication pain (initial claudication distance) and the maximally tolerated claudication pain (maximal claudication distance). |
Countries
Egypt
Contacts
Primary ContactReem M Farahat, student
Outcome results
None listed