Primary Sjögren Syndrome
Conditions
Brief summary
This study aims to establish a large sample cohort of patients with primary sjogren's syndrome, collect multi-omics information of patients with primary sjogren's syndrome, and construct disease diagnosis model and disease prognosis prediction model.
Interventions
None listed
Sponsors
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Beijing Hospital of Traditional Chinese Medicine
Shunyi Hospital, Beijing Traditional Chinese Medicine Hospital
China-Japan Friendship Hospital
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Meets the 2002 AECG or 2016 ACR/EULAR classification criteria of primary Sjögren's syndrome.
Exclusion criteria
* Comorbid connective tissue disease other than the disease under research. * Women who are pregnant or breastfeeding. * Combined severe cardiovascular or cerebrovascular disease, hepatic or renal failure, or severe malignant tumors. * Other conditions (e.g., cognitive impairment) that the investigators consider ineligible for enrollment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants with system involvement | Baseline , 6 months follow-up | System involvement determined from clinical diagnosis |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mortality | Baseline , 6 months follow-up | All-cause mortality |
| Number of participants with tumor | Baseline , 6 months follow-up | Tumor determined from clinical diagnosis |
| Number of participants with connective tissue disease | Baseline , 6 months follow-up | Connective tissue disease determined from clinical diagnosis |
Countries
China
Outcome results
None listed