Skip to content

Pain Measured by NRS and EEG in Acute Pulpitis

Measuring Pain Perception in Patients With Symptomatic Acute Pulpitis and Resistant to Inferior Alveolar Nerve Block Using NRS and Brain Waves

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06526572
Enrollment
50
Registered
2024-07-30
Start date
2023-07-01
Completion date
2025-01-31
Last updated
2024-07-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Pulpitis

Keywords

Acute pulpits, Electroencephalography, Numerical rate scale, Inferior Alveolar Nerve Block

Brief summary

The aim of the proposed study is to investigate and comprehensively understand pain perception in patients diagnosed with symptomatic acute pulpitis who are resistant to inferior alveolar nerve block (IANB). The study aims to achieve this by utilizing a dual approach that combines subjective self-reporting of pain intensity using the Numeric Rating Scale (NRS) with objective neurophysiological assessment through brain wave analysis using electroencephalography (EEG). By integrating these two methods, the study seeks to explore potential correlations between self-reported pain scores and neural responses recorded through EEG, providing insights into the pain experience of this specific patient population. Ultimately, the goal of the study is to enhance the understanding of pain perception mechanisms in individuals with symptomatic acute pulpitis resistant to IANB and potentially guide the development of more effective and personalized pain management strategies for these patients.

Interventions

DIAGNOSTIC_TESTBrain wave analysis using electroencephalography (EEG).

Asessment of pain with objective neurophysiological assessment through brain wave analysis using electroencephalography (EEG).

DIAGNOSTIC_TESTNumerical rate Scale (NRS)

Asessment of pain with the subjective numercal rate scale method (NRS

Sponsors

Cleveland Dental Institute
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

Adults aged \[18-50 years\]. Clinically diagnosed with symptomatic acute pulpitis based on dental examination and radiographic findings. Demonstrates resistance to inferior alveolar nerve block (IANB). Willing and able to provide informed consent to participate in the study. Able to communicate effectively in the language used for study procedures.

Exclusion criteria

Individuals with known neurological or psychiatric disorders affecting pain perception. Pregnant individuals or those breastfeeding at the time of the study. History of severe allergies or adverse reactions to local anesthetics or EEG gel. Presence of significant medical conditions that may contraindicate dental procedures or EEG recordings. Individuals taking medications that could significantly affect pain perception (e.g., strong analgesics, sedatives). Any contraindications for dental procedures or EEG recordings as determined by the study's dental and medical professionals. Inability to understand and follow study instructions.

Design outcomes

Primary

MeasureTime frameDescription
Electroencephalography (EEG)3 monthsChanges in alpha brain waves in patients with acute pulpitis and resistant to alveolar nerve block injection
Numerical Rate Scale (NRS)3 monthsMeasuring pain perception using NRS (Scale 0-10 where 0 is no pain and 10 is the most unbearable pain) in patients with acute pulpitis and resistant to alveolar nerve block injection.

Countries

United States

Contacts

Primary ContactAhmed I Basyoni
a.basyoni@cdiohio.org3612290038
Backup ContactAbdelrahman Zaghloul
a.zaghloul@cdiohio.org9016324289

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026