Multiple Sclerosis
Conditions
Keywords
Multiple Sclerosis, anaesthesia, relapse
Brief summary
The influence of anesthesia on the course of multiple sclerosis is poorly investigated and the literature is limited. The aim of this study is to investigate multiple sclerosis relapse after different types of anesthesia.
Detailed description
The influence of anesthesia on the course of multiple sclerosis is poorly investigated and the literature is limited. A possible relapse after neuraxial anesthesia, it is believed to be associated with local anesthetic's toxicity and concentration. The aim of this study is to investigate multiple sclerosis relapse after different types of anesthesia.
Interventions
PROCEDUREGeneral anaesthesia
Intravenous or volatile general anesthesia was preformed with different type of airway management (endotracheal tube, laryngeal mask and bag mask ventilation)
PROCEDURENeuraxial anaesthesia
spinal or epidural injections of local anesthetic with or without opioid
Sponsors
Varazdin General Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* multiple sclerosis * surgical procedure under general anaesthesia * surgical procedure under neuraxial anaesthesia
Exclusion criteria
* patients (medical records) with incomplete data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Multiple sclerosis relapse after 1 month | 1 month | Overall incidence of multiple sclerosis relapse after 1 month after anaesthesia |
| Multiple sclerosis relapse after 3 months | 3 months | Overall incidence of multiple sclerosis relapse after 3 months after anaesthesia |
| Multiple sclerosis relapse after 6 months | 6 months | Overall incidence of multiple sclerosis relapse after 6 months after anaesthesia |
| Multiple sclerosis relapse after 12 months | 12 months | Overall incidence of multiple sclerosis relapse after 12 months after anaesthesia |
Outcome results
None listed