Chronic Respiratory Disease
Conditions
Brief summary
In this project, the investigators aim to assess changes of physiological parameters obtained non-invasively through PPG and accelerometry signals between before and during LTOT (long-term oxygen therapy) and investigate if those changes are different in patients with worsening frailty and/or improving quality of life. For this, they will record optical (PPG) and accelerometry data via a datalogger on 40 patients undergoing LTOT and assess the PPG-derived physiological signals.
Interventions
OTHERLTOT
Patients with newly prescribed LTOT will be monitored for physiological changes
Sponsors
Insel Gruppe AG, University Hospital Bern
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age ≥ 18-year-old, and * Chronic respiratory disease including a) chronic obstructive pulmonary disease, b) interstitial lung disease, c) pulmonary hypertension, d) bronchiectasis, and * Prescribed new LTOT due to a chronic respiratory disease with resting and/or exertional hypoxemia, and * Able to speak/read/understand German or French, and * Willing and able to understand and provide signed informed consent
Exclusion criteria
* Pregnant or lactating women, or * Inability to follow the procedures/instructions of the study (e.g. due to language, psychological disorders, dementia, etc.), or * Patients having a subordination link to the investigators, or * Patients with isolated nocturnal oxygen therapy or LTOT prescription for a heart disease, sleep associated breathing disorder, neuromuscular disease or lung cancer, or * Known participation in another human research project (ClinO/HRO) that may affect the objectives of this study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Heart rate changes from before and during LTOT | From 1 week before start of LTOT to 1 month after start of LTOT | Record heart rate (BPM) to compare before and during LTOT |
| Respiratory rate changes from before and during LTOT | From 1 week before start of LTOT to 1 month after start of LTOT | Record respiratory rate (breaths per minute) to compare before and during LTOT |
| SpO2 changes from before and during LTOT | From 1 week before start of LTOT to 1 month after start of LTOT | Record SpO2 (%) to compare before and during LTOT |
Countries
Switzerland
Contacts
Primary ContactSabina Guler, PD Dr. med.
Outcome results
None listed