Intestinal Failure, Parenteral Nutrition
Conditions
Keywords
Quality of Life, Pediatric
Brief summary
We propose a multicenter prospective study on pediatric patients with intestinal failure (IF) who weaned off parenteral nutrition (PN).
Detailed description
Children with IF depend on PN. This is associated with frequent and various complications such as metabolic bone disease, micronutrient deficiencies and abnormal body composition. Due to advancements in care, many patients with IF are able to wean off PN; they are so called PN graduates. It is currently not well known how often complications do occur after weaning off PN, and which patients are at highest risk of developing these complications.
Interventions
OTHERWeaning off Parenteral Nutrition
pediatric intestinal failure patients who have been weaned off parenteral nutrition
Sponsors
The Hospital for Sick Children
Erasmus Medical Center
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
0 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
* Parenteral Nutrition graduates for at least 1 year, with a history of intestinal failure. * Age \<18 years at time of inclusion.
Exclusion criteria
* No consent provided.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Complications | From 1 year after weaning off PN to 18 years of age | Assess the frequency of nutritional complications including poor growth, micronutrient deficiencies, poor bone health, abnormal body composition, and delayed pubertal development in PN graduates. |
Countries
Canada
Outcome results
None listed