Subarachnoid Hemorrhage of Aneurysmal Cause
Conditions
Keywords
SAH (Subarachnoid Hemorrhage), Ruptured intracranial aneurysm, Modified Rankin score, Mortality, Patient autonomy, Patient dependence
Brief summary
The aim of our study is to analyze mortality and sequelae of subarachnoid hemorrhage of aneurysmal origin in hospitalized patients in Martinique. Predictive factors of poor prognosis will also be analyzed.
Detailed description
Subarachnoid hemorrhage is an uncommon pathology in the general population, with a worldwide incidence of 9 per 100,000 people/year, but with a non-negligible risk of sequelae in terms of impairments, activity limitations and participation restrictions of around 30%. Mortality remains high at 40%, despite increasingly specialized care. In addition, there are a number of objective, rapid assessment scores for autonomy and impairments, notably the modified Rankin score, which is not specific to subarachnoid hemorrhage, but which enables the study of patients' perceived quality of life. Certain factors predictive of bad patient outcome are known in the literature, but have been little studied in the population of Martinique.
Interventions
OTHERUsual patient care for patients hospitalized for subarachnoid hemorrhage of aneurysmal origin
During hospitalization (2013-2021), patients were managed after multidisciplinary consultation in accordance with national recommendations between resuscitators, neurosurgeons and neuroradiologists, depending on the severity of the initial management and the patient's comorbidities, either by interventional radiology, neurosurgery or medical treatment.
Sponsors
University Hospital Center of Martinique
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult (≥18 years) patients, * Admitted to University Hospital of Martinique with subarachnoid hemorrhage of aneurysmal origin between 01/01/2013 and 31/12/2021, * Informed patient/next-of-kin/treating physician consent for research participation.
Exclusion criteria
* Other causes of subarachnoid hemorrhage of non-aneurysmal origin (traumatic, arteriovenous malformation, cerebral tumor, cerebral thrombophlebitis).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evaluate mortality in patients hospitalized for subarachnoid hemorrhage of aneurysmal origin over a 9-year period (2013-2021) in Martinique. | 6 months | Mortality of subarachnoid hemorrhage of aneurysmal origin. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Evaluate the clinical outcome of these patients. | 6 months | Patient's clinical outcome (mortality, impairment of patient autonomy, impairment of patient's level of dependece), assessed with the modified Rankin score at discharge and at a distance from hospitalization (minimum delay: 2.5 years). |
| Analyze the factors associated with a significant impairment of autonomy and/or dependence. | 6 months | Predictive factors associated with significant impairment of patient autonomy and/or dependence (modified Rankin score = 4 or 5): age, degree of consciousness at the time of treatment (WFNS score), amount of blood in the meningeal spaces (Fisher score), aneurysm size |
| Analyze the factors associated with death. | 6 months | Predictive factors associated with death (modified Rankin score = 6): age, degree of consciousness at the time of treatment (WFNS score), amount of blood in the meningeal spaces (Fisher score), aneurysm size. |
| Analyze the factors associated with a poor prognosis (death AND/OR significant impairment of autonomy/dependence). | 6 months | Predictive factors associated with a poor prognosis (modified Rankin score ≥ 4: death AND/OR impaired patient autonomy and/or dependence): age, degree of consciousness at the time of treatment (WFNS score), amount of blood in the meningeal spaces (Fisher score), aneurysm size. |
Countries
Martinique
Contacts
Primary ContactMarie SABIA, PhD
Backup ContactPauline PICHOIS
Outcome results
None listed